Chimwai Chaweewan, Tongboonsong Punnee, Namramoon Orathai, Panyim Sakol, Attasart Pongsopee
Institute of Molecular Biosciences, Mahidol University, Salaya, Nakhon Pathom 73170, Thailand.
Institute of Molecular Biosciences, Mahidol University, Salaya, Nakhon Pathom 73170, Thailand; Department of Biochemistry, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
J Invertebr Pathol. 2016 Feb;134:23-26. doi: 10.1016/j.jip.2016.01.003. Epub 2016 Jan 5.
Penaeus monodon densovirus (PmDNV) is one of the major causes of stunted shrimp in the aquaculture industry in Thailand. Significant reductions in levels of PmDNV as assessed by PCR analysis of shrimp hepatopancreas were seen in both prophylactic and curative experiments after feeding shrimp with a formulated diet containing mixed inactivated bacteria harboring dsRNAs corresponding to the PmDNV ns1 and vp genes. Significant reductions of approximately 88% (prophylactic) and 64% (curative) of PmDNV were observed, suggesting that this diet has a high potential for application in commercial aquaculture for reducing PmDNV associated stunted growth of shrimp.
斑节对虾浓核病毒（PmDNV）是泰国水产养殖业中导致对虾生长迟缓的主要原因之一。在用含有携带与PmDNV ns1和vp基因相对应的dsRNA的混合灭活细菌的配方饲料喂养对虾后，在预防性和治疗性实验中，通过对虾肝胰腺进行PCR分析评估发现，PmDNV水平显著降低。观察到PmDNV显著降低了约88%（预防性）和64%（治疗性），这表明这种饲料在商业水产养殖中用于减少与PmDNV相关的对虾生长迟缓方面具有很高的应用潜力。
