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[0.75%布比卡因与0.75%布比卡因/2%甲哌卡因用于球后麻醉的效果比较及透明质酸酶添加效果]

[Comparison of the effect of 0.75% bupivacaine with 0.75% bupivacaine/2% mepivacaine in retrobulbar anesthesia and the effect of adding hyaluronidase].

作者信息

Lange W, von Denffer H, Honis M

出版信息

Fortschr Ophthalmol. 1989;86(4):312-5.

PMID:2676792
Abstract

For about 100 years retrobulbar injection of a local anesthetic has been regarded as being a safe, efficient anesthesia in cataract surgery. Today one of the most difficult steps in cataract surgery is the implantation of the IOL. Vis à tergo can lead to severe problems during this procedure. Therefore, the position of the iris (concave or convex) is an important result that depends on the quality of the block. Motor blockade and analgesia were also examined. The first investigation was done to answer the question of whether or not better results could be obtained by using a mixture of bupivacaine (0.75%) and mepicacaine (2%) or with bupivacaine alone. Injections were done observer-blind in all cases by the same operator. Pure bupivacaine provided the best anesthesia results. A second examination was done in the same way to measure the effects of the addition of hyaluronidase; motor blockade, analgesia und hypotonia of the globe were found to be significantly better with the addition of 75 IU of hyaluronidase.

摘要

在大约100年的时间里,球后注射局部麻醉剂一直被认为是白内障手术中一种安全、有效的麻醉方法。如今,白内障手术中最困难的步骤之一是人工晶状体的植入。术中的压力可能会在此过程中导致严重问题。因此,虹膜的位置(凹面或凸面)是一个重要结果,它取决于阻滞的质量。还对运动阻滞和镇痛进行了检查。首次研究旨在回答使用布比卡因(0.75%)和甲哌卡因(2%)的混合物或单独使用布比卡因是否能取得更好效果的问题。在所有情况下,注射均由同一名操作者在观察者不知情的情况下进行。单纯布比卡因提供了最佳的麻醉效果。以同样的方式进行了第二项检查,以测量添加透明质酸酶的效果;发现添加75国际单位透明质酸酶后,运动阻滞、镇痛和眼球低张力情况明显更好。

相似文献

1
[Comparison of the effect of 0.75% bupivacaine with 0.75% bupivacaine/2% mepivacaine in retrobulbar anesthesia and the effect of adding hyaluronidase].[0.75%布比卡因与0.75%布比卡因/2%甲哌卡因用于球后麻醉的效果比较及透明质酸酶添加效果]
Fortschr Ophthalmol. 1989;86(4):312-5.
2
Efficacy and safety of hyaluronidase 75 IU as an adjuvant to mepivacaine for retrobulbar anesthesia in cataract surgery.透明质酸酶75 IU作为甲哌卡因辅助剂用于白内障手术球后麻醉的有效性和安全性。
J Cataract Refract Surg. 2008 Nov;34(11):1966-9. doi: 10.1016/j.jcrs.2008.07.022.
3
[Loco-regional block in ophthalmic surgery: single drug or drug combination with hyaluronidase? Randomized prospective study].[眼科手术中的局部区域阻滞:单一药物还是与透明质酸酶联合用药?随机前瞻性研究]
Minerva Anestesiol. 1999 Nov;65(11):775-83.
4
[Anesthesia effects on ocular circulation. Synopsis of a study].[麻醉对眼循环的影响。一项研究的概要]
Fortschr Ophthalmol. 1991;88(5):577-87.
5
Sodium bicarbonate--an alternative to hyaluronidase in ocular anaesthesia for cataract surgery.碳酸氢钠——白内障手术眼部麻醉中透明质酸酶的替代物。
Indian J Ophthalmol. 2000 Dec;48(4):285-9.
6
Localization of local anesthetic solution by magnetic resonance imaging.通过磁共振成像对局部麻醉溶液进行定位
Ophthalmology. 2004 Feb;111(2):342-7. doi: 10.1016/j.ophtha.2003.05.026.
7
The effect of hyaluronidase on akinesia during cataract surgery.透明质酸酶对白内障手术中眼球运动不能的影响。
Ophthalmic Surg. 1989 May;20(5):325-6.
8
Retrobulbar anesthesia for cataract surgery: comparison of bupivacaine and bupivacaine/lidocaine combinations.
Can J Ophthalmol. 1985 Jun;20(4):131-4.
9
Caruncle single injection episcleral (Sub-tenon) anesthesia for cataract surgery: mepivacaine versus a lidocaine-bupivacaine mixture.
Anesth Analg. 2000 Jul;91(1):107-9. doi: 10.1097/00000539-200007000-00020.
10
Retrobulbar blockade of somatic, motor, and visual nerves by local anesthetics.局部麻醉药对躯体、运动及视觉神经的球后阻滞。
Ophthalmic Surg. 1993 Mar;24(3):171-80.

引用本文的文献

1
Use of hyaluronidase as an adjunct to local anaesthetic eye blocks to reduce intraoperative pain in adults.透明质酸酶作为局部麻醉性眼部阻滞辅助药物用于减轻成人术中疼痛。
Cochrane Database Syst Rev. 2018 Mar 2;3(3):CD010368. doi: 10.1002/14651858.CD010368.pub2.
2
Orbicular muscle akinesia in regional ophthalmic anaesthesia with pH-adjusted bupivacaine: effects of hyaluronidase and epinephrine.使用pH值调整的布比卡因进行局部眼科麻醉时轮匝肌运动不能:透明质酸酶和肾上腺素的影响
Can J Anaesth. 1993 Nov;40(11):1028-33. doi: 10.1007/BF03009472.
3
Hyaluronidase improves regional ophthalmic anaesthesia with etidocaine.
透明质酸酶可改善依替卡因的局部眼科麻醉效果。
Can J Anaesth. 1992 Nov;39(9):920-4. doi: 10.1007/BF03008340.