Hochreiter Bettina, Strahm Carol, Behrend Henrik
Department of Orthopaedic Surgery and Traumatology, Cantonal Hospital St. Gallen, 9007, St. Gallen, Switzerland.
Department of Infectious Diseases and Infection Control, Cantonal Hospital St. Gallen, 9007, St. Gallen, Switzerland.
Knee Surg Sports Traumatol Arthrosc. 2016 Oct;24(10):3115-3121. doi: 10.1007/s00167-016-3982-8. Epub 2016 Jan 14.
Treatment strategies for advanced knee osteoarthritis with coexistent joint infection are not well established. While in periprosthetic joint infection the two-stage approach has been studied extensively, only few case reports on two-stage total knee arthroplasty (TKA) for knee osteoarthritis with coexistent joint infection have been published. The purpose of this paper was to report on our method of implementing a two-stage TKA with intervening antibiotic-loaded articulating cement spacers and a short interval between first- and second-stage procedures to treat two patients with Staphylococcus aureus-infected end-stage knee osteoarthritis. Consistent infection eradication was found at a 1-year follow-up with postoperative range of motion and knee scores comparing favourably with those of other case series. Level of evidence V.
对于合并关节感染的晚期膝骨关节炎，其治疗策略尚未完全确立。虽然在人工关节周围感染中，两阶段治疗方法已得到广泛研究，但关于两阶段全膝关节置换术（TKA）治疗合并关节感染的膝骨关节炎的病例报告却很少。本文旨在报告我们采用两阶段TKA的方法，即在两阶段手术之间插入含抗生素的关节水泥间隔物，并缩短两阶段手术的间隔时间，以治疗两名金黄色葡萄球菌感染的终末期膝骨关节炎患者。在1年的随访中发现感染得到持续根除，术后活动范围和膝关节评分与其他病例系列相比具有优势。证据级别为V级。
