Pelham W E, Walker J L, Sturges J, Hoza J
J Am Acad Child Adolesc Psychiatry. 1989 Sep;28(5):773-6. doi: 10.1097/00004583-198909000-00021.
The effects of 0.3 mg/kg methylphenidate were compared for 12 ADD boys and 12 ADD girls participating in a summer treatment program for children with behavior and/or learning problems. Previous investigations have suggested that ADD girls may differ from ADD boys in some important respects. No information exists regarding whether the effects of the most common treatment for these children, methylphenidate, has comparable effects on boys and girls. The boys and girls were matched for age and IQ. The results revealed equivalent and beneficial effects of methylphenidate for both boys and girls. Methylphenidate therefore would appear to be as useful a treatment for ADD girls as for ADD boys.
对12名患注意力缺陷多动障碍（ADD）的男孩和12名患ADD的女孩进行了比较，这些孩子都参加了一个针对有行为和/或学习问题儿童的暑期治疗项目，所用药为0.3毫克/千克的哌甲酯。先前的研究表明，患ADD的女孩在某些重要方面可能与患ADD的男孩有所不同。目前尚无信息表明，这些孩子最常用的治疗药物哌甲酯对男孩和女孩的疗效是否相当。男孩和女孩在年龄和智商方面进行了匹配。结果显示，哌甲酯对男孩和女孩都有同等且有益的效果。因此，哌甲酯似乎对患ADD的女孩和患ADD的男孩一样有用。
