Meng Xia, Zhu Xinying, Chen Liping, Wu Jing, Liu Gaifang, Xia Bing
Department of Gastroenterology, The Third Hospital of Hebei Medical University Shijiazhuang 050051, China.
Department of Gastroenterology, Zhongnan Hospital, School of Medicine of Wuhan University Wuhan 430000, China.
Int J Clin Exp Med. 2015 Oct 15;8(10):19184-7. eCollection 2015.
Pyoderma gangrenosum (PG), an extra-intestinal manifestation of ulcerative colitis (UC), is extremely rare. Up to now, there is no any data reported the occurrence of PG in joints, especially in China. The management of PG associated with UC is a therapeutic challenge. Our report here showed that a female patient diagnosed as UC complained a pustule in the dorsal side of left wrist, primarily was diagnosed as bone tuberculosis. The pustule progressed rapidly into a severe painful necrolytic cutaneous ulcer with a pale purple irregular destructive ulcer edge, this patient was diagnosed by UC complicated with PG, and skin lesions were cured by UC treatment. Here, we for the first time present a case acquired correct diagnosis and successful treatment of UC associated with PG of articulations carpi. We report this case here in order to provide more information about this disease to more doctors, furthermore, to decrease the rates of misdiagnosis and missed diagnosis.
坏疽性脓皮病（PG）是溃疡性结肠炎（UC）的一种肠外表现，极为罕见。截至目前，尚无任何关于PG在关节部位发生的报道，尤其是在中国。PG合并UC的治疗是一项治疗挑战。我们在此报告，一名被诊断为UC的女性患者主诉左手腕背侧出现脓疱，最初被诊断为骨结核。脓疱迅速发展为严重疼痛的坏死性皮肤溃疡，溃疡边缘呈淡紫色不规则破坏性，该患者被诊断为UC合并PG，经UC治疗后皮肤病变治愈。在此，我们首次报告一例获得正确诊断并成功治疗的腕关节UC合并PG病例。我们在此报告此病例，以便向更多医生提供有关这种疾病的更多信息，此外，降低误诊和漏诊率。
