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青春期后隐睾症的个体化治疗指南

Individualized Treatment Guidelines for Postpubertal Cryptorchidism.

作者信息

Chung Jae Min, Lee Sang Don

机构信息

Department of Urology, Pusan National University School of Medicine, Pusan National University Yangsan Hospital, Yangsan, Korea.; Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Korea.

出版信息

World J Mens Health. 2015 Dec;33(3):161-6. doi: 10.5534/wjmh.2015.33.3.161. Epub 2015 Dec 23.

DOI:10.5534/wjmh.2015.33.3.161
PMID:26770935
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4709431/
Abstract

Cryptorchidism is a well-known congenital anomaly in children. However, its diagnosis is often delayed for reasons including patient unawareness or denial of abnormal findings in the testis. Moreover, it has been difficult to establish an optimal treatment strategy for postpubertal cryptorchidism, given the small number of patients. Unlike cryptorchidism in children, postpubertal cryptorchidism is associated with an increased probability of neoplasms, which has led orchiectomy to be the recommended treatment. However, routine orchiectomy should be avoided in some cases due to quality-of-life issues and the potential risk of perioperative mortality. Based on a literature review, this study proposes individualized treatment guidelines for postpubertal cryptorchidism.

摘要

隐睾症是儿童中一种众所周知的先天性异常。然而,其诊断往往会延迟,原因包括患者未意识到或否认睾丸存在异常发现。此外,鉴于患者数量较少,很难为青春期后隐睾症制定最佳治疗策略。与儿童隐睾症不同,青春期后隐睾症与肿瘤发生概率增加相关,这使得睾丸切除术成为推荐的治疗方法。然而,由于生活质量问题和围手术期死亡的潜在风险,在某些情况下应避免常规睾丸切除术。基于文献综述,本研究提出了青春期后隐睾症的个体化治疗指南。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9891/4709431/a19205c5bb50/wjmh-33-161-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9891/4709431/a19205c5bb50/wjmh-33-161-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9891/4709431/a19205c5bb50/wjmh-33-161-g001.jpg

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1
Individualized Treatment Guidelines for Postpubertal Cryptorchidism.青春期后隐睾症的个体化治疗指南
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The incidence and histological characteristics of intratubular germ cell neoplasia in postpubertal cryptorchid testis.青春期后隐睾睾丸内生殖细胞肿瘤的发病率及组织学特征
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[The evaluation of gonadal function in postpubertal patients treated for cryptorchism in childhood].[儿童期接受隐睾症治疗的青春期后患者的性腺功能评估]
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Stepwise mini-incision microdissection testicular sperm extraction in NOA patients with a history of cryptorchidism: a case-control study.对有隐睾病史的非梗阻性无精子症患者采用逐步小切口显微解剖睾丸取精术:一项病例对照研究。
Basic Clin Androl. 2023 Aug 17;33(1):21. doi: 10.1186/s12610-023-00196-w.
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Abdominal testicular vessel distribution in human fetuses - basis for fowler-Stephens surgery.

本文引用的文献

1
Clinical characteristics and treatment of cryptorchidism in adults: a single center experience.成人隐睾症的临床特征与治疗:单中心经验
World J Mens Health. 2014 Aug;32(2):110-5. doi: 10.5534/wjmh.2014.32.2.110. Epub 2014 Aug 26.
2
Risk of contralateral testicular cancer among men with unilaterally undescended testis: a meta analysis.单侧隐睾男性对侧睾丸癌的风险:一项荟萃分析。
Int J Cancer. 2009 Feb 1;124(3):687-9. doi: 10.1002/ijc.23936.
3
The frequency of undescended testis from birth to adulthood: a review.从出生到成年隐睾症的发生率:一篇综述
人体胎儿的腹侧睾丸血管分布 - Fowler-Stephens 手术的基础。
Int Braz J Urol. 2023 Nov-Dec;49(6):749-756. doi: 10.1590/S1677-5538.IBJU.2023.9909.
4
Classical Seminoma With Secondary Undescended Testis in an Elderly Patient: An Incidental Finding With a Penile Fracture.老年患者合并继发性隐睾的经典型精原细胞瘤:一例合并阴茎骨折的偶然发现
Cureus. 2022 Nov 26;14(11):e31924. doi: 10.7759/cureus.31924. eCollection 2022 Nov.
5
Dilemma on Indonesian adult with micropenis during COVID-19 pandemic: A case report and review article.新冠疫情期间一名印尼成年小阴茎患者的困境:病例报告及综述文章
Ann Med Surg (Lond). 2022 Aug;80:104244. doi: 10.1016/j.amsu.2022.104244. Epub 2022 Jul 31.
6
Azoospermic Men with a History of Cryptorchidism Treated by Orchiopexy Have Favorable Outcomes after Testicular Sperm Extraction: A Systematic Review and Meta-Analysis.接受睾丸固定术治疗的有隐睾病史的无精子症男性在睾丸精子提取后有良好结局:一项系统评价和荟萃分析
World J Mens Health. 2023 Jan;41(1):81-93. doi: 10.5534/wjmh.210198. Epub 2022 Mar 10.
7
Testicular arteries anatomy applied to fowler-sthephens surgery in high undescended testis - a narrative review.应用于高位未降睾丸的 Fowler-Stephens 手术的睾丸动脉解剖学:一项叙述性综述。
Int Braz J Urol. 2022 Jan-Feb;48(1):8-17. doi: 10.1590/S1677-5538.IBJU.2021.99.11.
Int J Androl. 2008 Feb;31(1):1-11. doi: 10.1111/j.1365-2605.2007.00770.x. Epub 2007 May 3.
4
Age at surgery for undescended testis and risk of testicular cancer.隐睾手术时的年龄与睾丸癌风险
N Engl J Med. 2007 May 3;356(18):1835-41. doi: 10.1056/NEJMoa067588.
5
Current management of the undescended testicle.隐睾的当前治疗方法
Semin Pediatr Surg. 2007 Feb;16(1):64-70. doi: 10.1053/j.sempedsurg.2006.10.009.
6
[Cryptorchidism in adults. About 81 cases].成人隐睾症。约81例
Tunis Med. 2005 Dec;83(12):742-5.
7
[Is necessary to practice orchiectomy in patients with post-puberal maldescended testes?].[青春期后睾丸未降的患者是否有必要进行睾丸切除术?]
Actas Urol Esp. 2005 Nov-Dec;29(10):969-73. doi: 10.1016/s0210-4806(05)73378-7.
8
Laparoscopic management of cryptorchidism in adults.成人隐睾症的腹腔镜治疗
Eur Urol. 2005 Sep;48(3):453-7; discussion 457. doi: 10.1016/j.eururo.2005.04.008. Epub 2005 Apr 25.
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Abnormalities of testicular descent.睾丸下降异常。
Cell Tissue Res. 2005 Oct;322(1):155-8. doi: 10.1007/s00441-005-1126-4. Epub 2005 Nov 3.
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Management of cryptorchism and risk of testicular cancer.隐睾症的管理与睾丸癌风险
Am J Epidemiol. 2003 Apr 1;157(7):602-5. doi: 10.1093/aje/kwg012.