Hosoki Maki, Nishigawa Keisuke, Miyamoto Youji, Ohe Go, Matsuka Yoshizo
Department of Stomatognathic Function and Occlusal Reconstruction, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
Department of Oral Surgery, Institute of Health Biosciences, Tokushima University Graduate School, Tokushima, Japan.
J Prosthodont Res. 2016 Jul;60(3):213-9. doi: 10.1016/j.jpor.2015.12.004. Epub 2016 Jan 8.
Titanium has been considered to be a non-allergenic material. However, several studies have reported cases of metal allergy caused by titanium-containing materials. We describe a 69-year-old male for whom significant pathologic findings around dental implants had never been observed. He exhibited allergic symptoms (eczema) after orthopedic surgery. The titanium screws used in the orthopedic surgery that he underwent were removed 1 year later, but the eczema remained. After removal of dental implants, the eczema disappeared completely.
Titanium is used not only for medical applications such as plastic surgery and/or dental implants, but also for paints, white pigments, photocatalysts, and various types of everyday goods. Most of the usage of titanium is in the form of titanium dioxide. This rapid expansion of titanium-containing products has increased percutaneous and permucosal exposure of titanium to the population.
In general, allergic risk of titanium material is smaller than that of other metal materials. However, we suggest that pre-implant patients should be asked about a history of hypersensitivity reactions to metals, and patch testing should be recommended to patients who have experienced such reactions.
钛一直被认为是一种无致敏性的材料。然而,多项研究报告了含钛材料导致金属过敏的病例。我们描述了一名69岁男性,其牙种植体周围从未观察到显著的病理表现。他在骨科手术后出现了过敏症状(湿疹)。他接受的骨科手术中使用的钛螺钉在1年后被取出,但湿疹仍未消退。牙种植体取出后,湿疹完全消失。
钛不仅用于整形手术和/或牙种植体等医疗应用,还用于涂料、白色颜料、光催化剂和各类日常用品。钛的大部分用途是以二氧化钛的形式存在。含钛产品的这种迅速扩张增加了钛经皮和经黏膜向人群的暴露。
一般来说,钛材料的过敏风险低于其他金属材料。然而,我们建议在植入前询问患者对金属的过敏反应史,对于有此类反应的患者应建议进行斑贴试验。