Tomasino Barbara, Gremese Michele
IRCCS "E. Medea," San Vito al Tagliamento, Italy.
Front Hum Neurosci. 2016 Jan 7;9:693. doi: 10.3389/fnhum.2015.00693. eCollection 2015.
We can predict how an object would look like if we were to see it from different viewpoints. The brain network governing mental rotation (MR) has been studied using a variety of stimuli and tasks instructions. By using activation likelihood estimation (ALE) meta-analysis we tested whether different MR networks can be modulated by the type of stimulus (body vs. non-body parts) or by the type of tasks instructions (motor imagery-based vs. non-motor imagery-based MR instructions). Testing for the bodily and non-bodily stimulus axis revealed a bilateral sensorimotor activation for bodily-related as compared to non-bodily-related stimuli and a posterior right lateralized activation for non-bodily-related as compared to bodily-related stimuli. A top-down modulation of the network was exerted by the MR tasks instructions with a bilateral (preferentially sensorimotor left) network for motor imagery- vs. non-motor imagery-based MR instructions and the latter activating a preferentially posterior right occipito-temporal-parietal network. The present quantitative meta-analysis summarizes and amends previous descriptions of the brain network related to MR and shows how it is modulated by top-down and bottom-up experimental factors.
我们可以预测，如果从不同视角观察一个物体，它会是什么样子。人们已经使用各种刺激和任务指令对控制心理旋转（MR）的大脑网络进行了研究。通过使用激活似然估计（ALE）元分析，我们测试了不同的MR网络是否会受到刺激类型（身体部位与非身体部位）或任务指令类型（基于运动想象的MR指令与非基于运动想象的MR指令）的调节。对身体和非身体刺激轴的测试显示，与非身体相关刺激相比，身体相关刺激会引发双侧感觉运动激活；与身体相关刺激相比，非身体相关刺激会引发右侧后外侧激活。MR任务指令对该网络产生自上而下的调节作用，基于运动想象的MR指令与非基于运动想象的MR指令分别激活双侧（优先激活左侧感觉运动区）网络和优先激活右侧枕颞顶叶后部网络。本定量元分析总结并修正了先前关于与MR相关的大脑网络的描述，并展示了它是如何受到自上而下和自下而上实验因素调节的。
