膀胱炎性肌纤维母细胞瘤中的ALK基因易位：一例报告
ALK Gene Translocation in Inflammatory Myofibroblastic Tumor of the Urinary Bladder: A Case Report.
作者信息
Takagi Kimiaki, Takai Manabu, Kameyama Koji, Horie Kengo, Kikuchi Mina, Kato Taku, Mizutani Kosuke, Seike Kensaku, Tsuchiya Tomohiro, Yasuda Mitsuru, Yokoi Shigeaki, Suzui Natsuko, Nakano Masahiro, Deguchi Takashi
机构信息
Department of Urology, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu city, Gifu 501-1194, Japan.
Pathology Division, Gifu University Hospital, 1-1 Yanagido, Gifu city, Gifu 501-1194, Japan.
出版信息
Urol Case Rep. 2015 Jul 2;3(5):138-40. doi: 10.1016/j.eucr.2015.06.003. eCollection 2015 Sep.
A 26-year-old woman with gross hematuria was seen in a previous hospital. Magnetic resonance imaging (MRI) showed a tumor at the dome of the urinary bladder with invasion outside of the bladder wall. The patient underwent transurethral resection of the bladder tumor (TUR-BT). From the result of the pathological examination, the tumor was suggested to be carcinosarcoma of the bladder. The patient was then referred to our hospital for treatment. We performed radical cystectomy and ileal conduit diversion. Pathological examination of the excised specimen revealed an inflammatory myofibroblastic tumor as the basis for immunostaining of anaplastic lymphoma kinase (ALK).
一名26岁肉眼血尿的女性曾在之前的医院就诊。磁共振成像（MRI）显示膀胱顶部有一个肿瘤，侵犯膀胱壁外。患者接受了经尿道膀胱肿瘤切除术（TUR-BT）。根据病理检查结果，肿瘤提示为膀胱癌肉瘤。随后患者转诊至我院接受治疗。我们进行了根治性膀胱切除术和回肠膀胱术。切除标本的病理检查显示为炎性肌纤维母细胞瘤，作为间变性淋巴瘤激酶（ALK）免疫染色的基础。
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