Center for Free-Electron Laser Science, DESY , Notkestr. 85, 22607 Hamburg, Germany.
SLAC National Accelerator Laboratory , 2575 Sand Hill Road, Menlo Park, California 94025, USA.
Struct Dyn. 2015 Apr 21;2(4):041701. doi: 10.1063/1.4918726. eCollection 2015 Jul.
Intense femtosecond x-ray pulses from free-electron laser sources allow the imaging of individual particles in a single shot. Early experiments at the Linac Coherent Light Source (LCLS) have led to rapid progress in the field and, so far, coherent diffractive images have been recorded from biological specimens, aerosols, and quantum systems with a few-tens-of-nanometers resolution. In March 2014, LCLS held a workshop to discuss the scientific and technical challenges for reaching the ultimate goal of atomic resolution with single-shot coherent diffractive imaging. This paper summarizes the workshop findings and presents the roadmap toward reaching atomic resolution, 3D imaging at free-electron laser sources.
飞秒级强度的 X 射线脉冲源自自由电子激光源,可实现单个粒子的单次成像。林可先纳coherent light source(LCLS)的早期实验在该领域取得了快速进展,迄今为止,相干衍射图像已从生物样本、气溶胶和量子系统中以几十纳米的分辨率记录下来。2014 年 3 月,LCLS 举办了一次研讨会,讨论实现单次相干衍射成像原子分辨率的科学和技术挑战。本文总结了研讨会的成果,并提出了在自由电子激光源实现原子分辨率、三维成像的路线图。