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普通人群中银屑病患者的心肺适能

Cardiorespiratory Fitness Among Individuals With Psoriasis in the General Population.

作者信息

Wilson Patrick B

机构信息

Dept of Human Movement Sciences, Old Dominion University, Norfolk, VA.

出版信息

J Phys Act Health. 2016 Jul;13(7):771-5. doi: 10.1123/jpah.2015-0150. Epub 2016 Jan 22.

Abstract

BACKGROUND

Psoriasis confers risk for cardiometabolic disorders. Cardiorespiratory fitness is inversely associated with risk of cardiometabolic disorders in other populations, but limited data have been published assessing cardiorespiratory fitness among individuals with psoriasis. This investigation aimed to: 1) assess cardiorespiratory fitness among individuals with psoriasis in the general population; and 2) compare levels to individuals without psoriasis.

METHODS

A secondary data analysis from the 2003-2004 National Health and Nutritional Examination Survey was performed. Cardiorespiratory fitness was assessed with a treadmill test, while measures of psoriasis severity included rating of psoriasis as a life problem and body surface area involvement.

RESULTS

Twenty-six of 1093 participants reported a psoriasis diagnosis (population weighted prevalence 2.9%). Individuals with psoriasis had lower cardiorespiratory fitness compared with individuals without psoriasis (36.2 vs. 39.1 mL·kg-1·min-1, P = .009). No differences in self-reported or accelerometer physical activity were found by psoriasis diagnosis. Cardiorespiratory fitness was not significantly lower in those reporting high life impairment or body surface area involvement.

CONCLUSIONS

Cardiorespiratory fitness may be lower in individuals with psoriasis and these differences may not be explained by self-reported disease severity measures or physical activity. Future studies should examine whether validated measures of psoriasis severity predict lower cardiorespiratory fitness.

摘要

背景

银屑病会增加发生心脏代谢紊乱的风险。在其他人群中,心肺适能与心脏代谢紊乱风险呈负相关,但关于银屑病患者心肺适能的评估数据有限。本研究旨在:1)评估普通人群中银屑病患者的心肺适能;2)将其与非银屑病患者的水平进行比较。

方法

对2003 - 2004年国家健康与营养检查调查的二次数据分析。通过跑步机测试评估心肺适能,银屑病严重程度的测量指标包括将银屑病评定为生活问题以及累及的体表面积。

结果

1093名参与者中有26人报告患有银屑病(人群加权患病率2.9%)。与非银屑病患者相比,银屑病患者的心肺适能较低(36.2对39.1 mL·kg-1·min-1,P = .009)。根据银屑病诊断情况,在自我报告或通过加速度计测量的身体活动方面未发现差异。报告有高度生活障碍或体表面积累及的患者,其心肺适能并未显著降低。

结论

银屑病患者的心肺适能可能较低,这些差异可能无法通过自我报告的疾病严重程度指标或身体活动来解释。未来的研究应检查经过验证的银屑病严重程度指标是否能预测较低的心肺适能。

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