Marcano-Belisario José S, Gupta Ajay K, O'Donoghue John, Morrison Cecily, Car Josip
Global eHealth Unit, Department of Primary Care and Public Health, Imperial College London, London, UK.
National Heart & Lung Institute, Imperial College London, London, UK.
BMJ Open. 2016 Jan 22;6(1):e009930. doi: 10.1136/bmjopen-2015-009930.
Depression is one of the most common mental health disorders that may affect women during pregnancy. The prompt identification of this disorder, and the provision of treatment, may help to reduce the likelihood of post-partum depression, prevent severe forms of the disease, and reduce its intergenerational impact. Despite women's repeated encounters with health services throughout their antenatal care, depression often goes undiagnosed. This is one area where mobile health could prove useful. We will assess the feasibility of using tablets to incorporate depression screening into antenatal pathways. We will also assess if survey layout could affect the quality of the data collected through these devices.
We will test the feasibility of using iPad Airs for the administration of the Whooley questions and the Edinburgh Postnatal Depression Scale (EPDS) to pregnant women attending antenatal clinics in England. We will assess the impact of survey layout on the quality of the responses given to these screening scales using a parallel, randomised controlled study design. We will calculate the positive predictive value, the negative predictive value and the false omission rate of the Whooley questions in comparison with the EPDS. We will calculate differences in data equivalence, time needed to complete the surveys, break-off rates, data completeness and requests for help between the 2 experimental groups: using all questions in one screen and navigation by vertical scrolling, or a single question per screen and navigation by multiple pages.
This study has been approved by the National Research Ethics Service Committee South East Coast--Surrey. Our findings will be disseminated through academic peer-reviewed publications, conferences and discussion with peers.
抑郁症是孕期可能影响女性的最常见心理健康障碍之一。及时识别这种障碍并提供治疗，可能有助于降低产后抑郁症的发生几率，预防该疾病的严重形式，并减少其代际影响。尽管女性在整个产前护理过程中多次接触医疗服务，但抑郁症往往未被诊断出来。在这方面，移动健康可能会发挥作用。我们将评估使用平板电脑将抑郁症筛查纳入产前诊疗流程的可行性。我们还将评估调查问卷的布局是否会影响通过这些设备收集的数据质量。
我们将测试使用iPad Air对在英格兰产前诊所就诊的孕妇进行Whooley问题调查和爱丁堡产后抑郁量表（EPDS）评估的可行性。我们将采用平行随机对照研究设计，评估调查问卷布局对这些筛查量表所获回答质量的影响。我们将计算Whooley问题相对于EPDS的阳性预测值、阴性预测值和漏诊率。我们将计算两个实验组之间在数据等效性、完成调查所需时间、中断率、数据完整性和求助请求方面的差异，这两个实验组分别是：在一个屏幕上显示所有问题并通过垂直滚动进行导航，或者每个屏幕显示一个问题并通过多页进行导航。
本研究已获得国家研究伦理服务委员会东南海岸——萨里委员会的批准。我们的研究结果将通过学术同行评审出版物、会议以及与同行的讨论进行传播。
