Mohamad Yusuff Aza Sherin, Tang Li, Binns Colin W, Lee Andy H
School of Medicine, University Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia.
School of Public Health, Curtin University, Perth, WA, Australia.
Women Birth. 2015 Mar;28(1):25-9. doi: 10.1016/j.wombi.2014.11.002. Epub 2014 Nov 24.
Postnatal depression can have serious consequences for both the mother and infant. However, epidemiological data required to implement appropriate early prevention are still lacking in Malaysia.
To investigate the prevalence of postnatal depression within six months postpartum and associated risk factors among women in Sabah, Malaysia.
A prospective cohort study of 2072 women was conducted in Sabah during 2009-2010. Participants were recruited at 36-38 weeks of gestation and followed up at 1, 3 and 6 months postpartum. The presence of depressive symptoms was assessed using the validated Malay version of the Edinburgh Postnatal Depression Scale. Logistic regression analyses were performed to ascertain risk factors associated with postnatal depression.
Overall, 14.3% of mothers (95% confidence interval (CI) 12.5-16.2%) had experienced depression within the first six months postpartum. Women depressed during pregnancy (odds ratio (OR) 3.71, 95% CI 2.46-5.60) and those with consistent worries about the newborn (OR 1.68, 95% CI 1.16-2.42) were more likely to suffer from depression after childbirth. Women whose husband assisted with infant care (OR 0.43, 95% CI 0.20-0.97) and mothers who were satisfied with their marital relationship (OR 0.27, 95% CI 0.09-0.81) appeared to incur a reduced risk of postnatal depression.
A substantial proportion of mothers suffered from postnatal depression in Sabah, Malaysia. Screening and intervention programmes targeting vulnerable subgroups of women during antenatal and early postpartum periods are recommended to deal with the problem.
产后抑郁症对母亲和婴儿都会产生严重后果。然而，马来西亚仍缺乏实施适当早期预防所需的流行病学数据。
调查马来西亚沙巴州产后六个月内产后抑郁症的患病率及相关危险因素。
2009年至2010年在沙巴州对2072名女性进行了一项前瞻性队列研究。参与者在妊娠36 - 38周时招募，并在产后1个月、3个月和6个月进行随访。使用经过验证的马来语版爱丁堡产后抑郁量表评估抑郁症状的存在情况。进行逻辑回归分析以确定与产后抑郁症相关的危险因素。
总体而言，14.3%的母亲（95%置信区间（CI）12.5 - 16.2%）在产后头六个月内经历过抑郁症。孕期抑郁的女性（优势比（OR）3.71，95% CI 2.46 - 5.60）以及一直担心新生儿的女性（OR 1.68，95% CI 1.16 - 2.42）产后更易患抑郁症。丈夫协助照顾婴儿的女性（OR 0.43，95% CI 0.20 - 0.97）以及对婚姻关系满意的母亲（OR 0.27，95% CI 0.09 - 0.81）产后患抑郁症的风险似乎降低。
在马来西亚沙巴州，相当一部分母亲患有产后抑郁症。建议在产前和产后早期针对弱势女性亚组开展筛查和干预项目以解决该问题。
