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腹腔镜与开放性膀胱切除术治疗膀胱癌的比较:单中心110例病例报告

Comparison of laparoscopic and open cystectomy for bladder cancer: a single center of 110 cases report.

作者信息

Zheng Wei, Li Xuesong, Song Gang, Zhang Zheng, Yu Wei, Gong Kan, Song Yi, Zhang Qian, He Zhisong, Guo Yinglu, Zhou Liqun

机构信息

Department of Urology, Peking University First Hospital, Institute of Urology, Peking University, National Urological Cancer Center, Beijing 100034, China.

出版信息

Transl Androl Urol. 2012 Mar;1(1):4-8. doi: 10.3978/j.issn.2223-4683.2012.02.01.

Abstract

PURPOSE

We compared the operative time, complications, blood loss, total cost, and hospital days of laparoscopic cystectomy vs. open cystectomy for bladder cancer.

MATERIALS AND METHODS

This retrospective, nonrandomized study was conducted between January 2004 and March 2011 on 110 patients (17 women and 93 men) who underwent radical cystectomy for bladder cancer. A total of 45 cystectomies were performed laparoscopically and 65 by open surgery. Mean patient age was 62.9±10.4 years. The age, gender, American Society of Anesthesiologists score, histopathological results etc. were reviewed in this article.

RESULTS

Intraoperative blood loss was significantly lower in the laparoscopic surgery group (821±776 vs. 1112±706 mL, P=0.044) while operative time was significantly lower in the open surgery group (376±90 vs. 445±119 min, P=0.001). The total costs were also significantly lower in the open surgery group 51,726±13,589 yuan (about $8000) vs. 63,053±19,378 yuan (about $10,000), P<0.001). There was no statistically significant difference in complication rates, postoperative days in hospital between the two groups.

CONCLUSIONS

Laparoscopic cystectomy can reduce intraoperative blood loss significantly. Open cystectomy requires less operative time and has a lower cost than laparoscopic cystectomy for bladder cancer. There was no statistically significant difference in postoperative complication rates in the hospital between the two groups.

摘要

目的

我们比较了腹腔镜膀胱切除术与开放性膀胱切除术治疗膀胱癌的手术时间、并发症、失血量、总费用及住院天数。

材料与方法

这项回顾性、非随机研究于2004年1月至2011年3月对110例行膀胱癌根治性膀胱切除术的患者(17名女性和93名男性)进行。共45例膀胱切除术通过腹腔镜进行,65例通过开放手术进行。患者平均年龄为62.9±10.4岁。本文回顾了年龄、性别、美国麻醉医师协会评分、组织病理学结果等。

结果

腹腔镜手术组术中失血量显著更低(821±776 vs. 1112±706 mL,P = 0.044),而开放手术组手术时间显著更低(376±90 vs. 445±119分钟,P = 0.001)。开放手术组的总费用也显著更低,为51,726±13,589元(约8000美元),而腹腔镜手术组为63,053±19,378元(约10,000美元),P<0.001。两组并发症发生率、术后住院天数无统计学显著差异。

结论

腹腔镜膀胱切除术可显著减少术中失血量。对于膀胱癌,开放性膀胱切除术所需手术时间更少且费用低于腹腔镜膀胱切除术。两组术后医院并发症发生率无统计学显著差异。

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[Laparoscopic radical cystectomy in elderly patients with bladder cancer: feasibility and evaluation of morbidity].
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本文引用的文献

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Laparoscopic assisted radical cystectomy with ileal neobladder: a comparison with the open approach.
J Urol. 2004 Aug;172(2):489-93. doi: 10.1097/01.ju.0000129662.83162.2e.
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Eur Urol. 2002 Feb;41(2):105-12. doi: 10.1016/s0302-2838(01)00026-4.
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Urologic laparoscopy.泌尿外科腹腔镜检查
Surg Oncol Clin N Am. 2001 Jul;10(3):571-8.
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J Urol. 1980 May;123(5):640-3. doi: 10.1016/s0022-5347(17)56073-5.
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