Bélec L, Gherardi R, Georges A J, Schüller E, Vuillecard E, Di Costanzo B, Martin P M
Institut Pasteur, Bangui, Central African Republic.
J Neurol. 1989 Oct;236(7):411-4. doi: 10.1007/BF00314900.
Four cases of infranuclear facial palsy associated with infection by the human immunodeficiency virus in young heterosexual African patients are reported. Two cases were healthy HIV carriers, one patient manifested AIDS-related complex, and one case fulfilled the CDC criteria for AIDS. Two patients had a typical Bell's palsy, one presented with manifest cephalic Herpes zoster infection and one, who suffered from facial diplegia, could be considered to have a cephalic form of Guillain-Barré syndrome. A review of the literature confirmed that peripheral facial palsy can occur at any stage of HIV infection and in various clinical contexts. In stages I and II of the HIV infection, patients may develop either Bell's palsy or Guillain-Barré syndrome. In stages III and IV, when the cellular immunity has begun to decline, Herpes zoster-related facial paralysis, seventh cranial nerve involvement secondary to meningeal lymphomatosis, and peripheral facial paralysis as one aspect of widespread chronic peripheral neuropathy may also occur.
报告了4例年轻的非洲异性恋患者感染人类免疫缺陷病毒后发生的核下性面瘫。2例为健康的HIV携带者,1例表现为艾滋病相关综合征,1例符合美国疾病控制与预防中心(CDC)的艾滋病标准。2例患者患有典型的贝尔氏面瘫,1例出现明显的头部带状疱疹感染,1例患有双侧面瘫,可被认为患有头部型吉兰-巴雷综合征。文献回顾证实,周围性面瘫可发生于HIV感染的任何阶段及各种临床情况。在HIV感染的I期和II期,患者可能发生贝尔氏面瘫或吉兰-巴雷综合征。在III期和IV期,当细胞免疫开始下降时,还可能发生与带状疱疹相关的面瘫、脑膜淋巴瘤继发的第七颅神经受累以及作为广泛慢性周围神经病变一部分的周围性面瘫。