Hou Chen-Pang, Lin Yu-Hsiang, Hsu Yu-Chao, Chen Chien-Lun, Chang Phei-Lang, Tsui Ke-Hung
From the Department of Urology, Chang Gung Memorial Hospital at Linkou (K-HT, P-LC); School of Medicine, Chang Gung University (K-H T, P-LC, C-PH, Y-HL, Y-CH, C-LC); Kwei-Shan, Tao-Yuan, Taiwan.
Medicine (Baltimore). 2016 Jan;95(3):e2349. doi: 10.1097/MD.0000000000002349.
Robot-assisted partial nephrectomy (RAPN) has gradually become a popular minimally invasive nephron-sparing surgical option for small renal tumors. Ischemic injury should be minimized because it impacts renal function outcomes following partial nephrectomy. Herein, the authors detail the technique and present initial perioperative outcomes of our novel harmonic scalpel "drilling and clamping" method to implement zero-ischemic RAPN. The authors prospectively collected baseline and perioperative data of patients who underwent zero ischemic RAPN performed by our harmonic scalpel "drilling and clamping" method. From April 2012 to December 2014, a total of 19 consecutive zero ischemic RAPN procedures were performed by a single surgeon. For 18 of the 19 patients, RAPN using our harmonic scalpel "Drilling and Clamping" method was successfully completed without the need for hilar clamping. The median tumor size was 3.4 cm (range: 1.8-6.2); operative time was 3.2 hours (range: 1.9-4.5); blood loss was 100 mL (range: 30-950); and postoperative hospital stay was 4 days (3-26). One patient required intraoperative blood transfusion. Two patients had intra or postoperative complications: 1 was converted to traditional laparotomy because of massive bleeding, whereas another had postoperative stress ulcer. Pathology confirmed renal cell carcinoma in 13 patients (63.2%), angiomyolipoma in 6 patients: (31.5%), and oncocytoma in 1 patient (5.3%). Mean pre- and postoperative serum creatinine (0.82 mg/dL and 0.85 mg/dL, respectively), estimated glomerular filtration rate (84.12 and 82.18, respectively), and hemoglobin (13.27 g/dL and 12.71 g/dL, respectively) were comparable. The authors present a novel zero-ischemic technique for RAPN. They believe that this technique is feasible and reproducible.
机器人辅助部分肾切除术(RAPN)已逐渐成为治疗小肾肿瘤的一种流行的微创保肾手术选择。应尽量减少缺血性损伤,因为它会影响部分肾切除术后的肾功能结果。在此,作者详细介绍了我们新颖的谐波手术刀“钻孔和夹闭”方法的技术,并展示了其初始围手术期结果,以实现零缺血性RAPN。作者前瞻性收集了采用我们的谐波手术刀“钻孔和夹闭”方法进行零缺血性RAPN患者的基线和围手术期数据。2012年4月至2014年12月,一名外科医生连续进行了19例零缺血性RAPN手术。19例患者中的18例,使用我们的谐波手术刀“钻孔和夹闭”方法成功完成了RAPN,无需肾门夹闭。肿瘤中位数大小为3.4厘米(范围:1.8 - 6.2厘米);手术时间为3.2小时(范围:1.9 - 4.5小时);失血量为100毫升(范围:30 - 950毫升);术后住院时间为4天(3 - 26天)。1例患者术中需要输血。2例患者有术中或术后并发症:1例因大出血转为传统开腹手术,另1例有术后应激性溃疡。病理证实13例患者为肾细胞癌(63.2%),6例为血管平滑肌脂肪瘤(31.5%),1例为嗜酸细胞瘤(5.3%)。术前和术后血清肌酐均值(分别为0.82毫克/分升和0.85毫克/分升)、估计肾小球滤过率(分别为84.12和82.18)以及血红蛋白(分别为13.27克/分升和12.71克/分升)具有可比性。作者介绍了一种新颖的RAPN零缺血技术。他们认为该技术可行且可重复。