Sarganas Giselle, Neuhauser Hannelore K
Department of Epidemiology and Health Monitoring, Robert Koch Institute, Berlin, Germany.
DZHK, German Center for Cardiovascular Research, Partner Site, Berlin, Germany.
Hypertens Res. 2016 Jun;39(6):457-66. doi: 10.1038/hr.2016.5. Epub 2016 Jan 28.
Hypertension is a major risk factor for cardiovascular morbidity; therefore, its control is very important. International Guidelines recommend the same hypertension management in men and women; however, studies suggest that management of hypertension differs. This study explores gender-age disparities in the management and control of hypertension in Germany in 1998 and 2008-2011. Data from the German Health Examination Surveys (GNHIES98 1998, n=7124 and DEGS1 2008-2011, n=7988, age 18-79 years), including standardized blood pressure measurements and Anatomical Therapeutic Chemical medication codes, were analyzed by gender and two age groups. For 1998 and 2008-2011 in Germany, the gender gap in hypertension management persisted without significant changes. Hypertensive men in 2008-2011 had lower awareness of their condition (78.3 vs. 86.8%), less treatment for hypertension (65.3 vs. 79.2%), less control of hypertension (45.4 vs. 57.5%) and less treatment among those aware of their condition (83.9 vs. 91.5%) than did women. These gender differences were greater in younger compared with older adults (18-54 years vs. 55-79 years). No gender differences were observed in control of hypertension among those treated in 1998; however, subsequent improvement was less in younger men compared with the other age-gender groups, leading to a new gender gap in 18-54-year olds (women 84.8%, men 63.9%). Younger women used more β-blockers and less angiotensin-converting enzyme inhibitors (ACEI) than younger men. Factors positively associated with control among those treated for hypertension in the younger group were being a woman, using β-blockers or using ACEI, or angiotensin-receptor blockers. In the older group, diabetes was negatively associated with control of hypertension, whereas having cardiovascular comorbidities was positively associated. Gender disparities in hypertension management and control still exist in Germany but may be masked because they are age-dependent.
高血压是心血管疾病发病的主要危险因素;因此,对其进行控制非常重要。国际指南建议对男性和女性采用相同的高血压管理方法;然而,研究表明高血压的管理存在差异。本研究探讨了1998年以及2008 - 2011年德国高血压管理与控制方面的性别 - 年龄差异。分析了来自德国健康检查调查(1998年的GNHIES98,n = 7124;2008 - 2011年的DEGS1,n = 7988,年龄在18 - 79岁)的数据,包括标准化血压测量值和解剖治疗化学药物编码,并按性别和两个年龄组进行了分析。在德国,1998年以及2008 - 2011年,高血压管理方面的性别差距持续存在且无显著变化。2008 - 2011年的高血压男性对自身病情的知晓率较低(78.3%对86.8%),接受高血压治疗的比例较低(65.3%对79.2%),高血压得到控制的比例较低(45.4%对57.5%),在知晓自身病情的人群中接受治疗的比例也较低(83.9%对91.5%),均低于女性。与老年人(55 - 79岁)相比,这些性别差异在年轻人(18 - 54岁)中更大。1998年接受治疗的人群中,在高血压控制方面未观察到性别差异;然而,与其他年龄 - 性别组相比,年轻男性随后的改善较小,导致18 - 54岁人群中出现了新的性别差距(女性为84.8%,男性为63.9%)。年轻女性比年轻男性更多地使用β受体阻滞剂,更少地使用血管紧张素转换酶抑制剂(ACEI)。在年轻组中,接受高血压治疗的人群中与血压控制呈正相关的因素包括女性、使用β受体阻滞剂或使用ACEI或血管紧张素受体阻滞剂。在老年组中,糖尿病与高血压控制呈负相关,而患有心血管合并症则与高血压控制呈正相关。德国在高血压管理与控制方面的性别差异仍然存在,但可能因年龄依赖性而被掩盖。