培养阴性心内膜炎继发坏死性抗中性粒细胞胞浆抗体阳性肾小球肾炎
Necrotizing ANCA-Positive Glomerulonephritis Secondary to Culture-Negative Endocarditis.
作者信息
Van Haare Heijmeijer Sophie, Wilmes Dunja, Aydin Selda, Clerckx Caroline, Labriola Laura
机构信息
Department of Nephrology, Clinique Saint-Pierre, Ottignies, Belgium.
Department of Internal Medicine, Cliniques universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium.
出版信息
Case Rep Nephrol. 2015;2015:649763. doi: 10.1155/2015/649763. Epub 2015 Dec 27.
Abstract
Infective endocarditis (IE) and small-vessel vasculitis may have similar clinical features, including glomerulonephritis. Furthermore the association between IE and ANCA positivity is well documented, making differential diagnosis between IE- and ANCA-associated vasculitis particularly difficult, especially in case of culture-negative IE. We report on one patient with glomerulonephritis secondary to culture-negative IE caused by Bartonella henselae which illustrates this diagnostic difficulty.
摘要
感染性心内膜炎（IE）和小血管血管炎可能具有相似的临床特征，包括肾小球肾炎。此外，IE与抗中性粒细胞胞浆抗体（ANCA）阳性之间的关联已有充分记录，这使得IE相关性血管炎和ANCA相关性血管炎的鉴别诊断尤为困难，尤其是在血培养阴性的IE病例中。我们报告了1例由汉赛巴尔通体引起的血培养阴性IE继发肾小球肾炎的患者，该病例说明了这种诊断困难。
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