激光散射细胞测量法评估白塞氏葡萄膜炎患者的眼内炎症
Evaluation of Intraocular Inflammation with Laser Flare Photometry in Behçet Uveitis.
作者信息
Yalcindag Fatime Nilufer, Bingol Kiziltunc Pinar, Savku Esra
机构信息
a Ankara University , Faculty of Medicine, Department of Ophthalmology , Ankara , Turkey.
b Islahiye State Hospital , Gaziantep , Turkey.
出版信息
Ocul Immunol Inflamm. 2017 Feb;25(1):41-45. doi: 10.3109/09273948.2015.1108444. Epub 2016 Jan 30.
PURPOSE
To evaluate the association between intraocular inflammation and laser flare photometry measurements in Behçet disease.
METHODS
In total, 45 patients were included in the study. The retrospective chart reviews of patients were performed. The flare levels were compared with the grade of anterior chamber cells, the presence of vitreous cells, the complications of uveitis, and fluorescein angiography scores.
RESULTS
The attack group had higher flare intensity; the flare levels were higher in both groups compared with the values of healthy controls. The flare levels were related to the grade of the anterior chamber cells, the presence of vitreous cells and the fluorescein angiography scores. Patients with optic atrophy and/or maculopathy also had higher values. Higher flare values were correlated with poor vision.
CONCLUSIONS
Laser flare photometry may reduce the necessity of fluorescein angiography in monitoring subclinical inflammation and may be an indicator of posterior segment activity when fluorescein angiography is not applicable.
目的
评估白塞病患者眼内炎症与激光flare光度测量之间的关联。
方法
本研究共纳入45例患者。对患者进行回顾性病历审查。将flare水平与前房细胞分级、玻璃体细胞的存在情况、葡萄膜炎并发症以及荧光素血管造影评分进行比较。
结果
发作组的flare强度更高；与健康对照组的值相比，两组的flare水平均更高。flare水平与前房细胞分级、玻璃体细胞的存在情况以及荧光素血管造影评分相关。患有视神经萎缩和/或黄斑病变的患者也有更高的值。更高的flare值与视力差相关。
结论
激光flare光度测量在监测亚临床炎症时可能会减少荧光素血管造影的必要性，并且在荧光素血管造影不适用时可能是后段活动的一个指标。
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