Ochi Takehiro, Yamada Azusa, Naganuma Yuki, Nishina Noriko, Koyama Hironari
Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1-6, Kashima 2-chome, Yodogawa-ku, Osaka 532-8514, Japan.
J Vet Med Sci. 2016 Jun 1;78(5):889-93. doi: 10.1292/jvms.15-0502. Epub 2016 Feb 1.
To determine the effect of long-distance (approximately 600 km) road transportation on the blood biochemistry of laboratory animals, we investigated the changes in serum biochemical parameters in healthy cynomolgus monkeys and beagle dogs transported by truck from Osaka to Tsukuba, Japan. The concentrations of serum cortisol, total bilirubin and aspartate aminotransferase in monkeys increased during transportation. Serum cortisol and total bilirubin levels in dogs also increased during transportation, but serum triglyceride decreased. Serum parameter values in truck-transported monkeys and dogs returned to baseline levels within two weeks following arrival. Taken together, these results suggest that a two-week acclimation period is the minimum duration required for adaptation following road transportation.
为了确定长途（约600公里）公路运输对实验动物血液生化指标的影响，我们调查了从日本大阪用卡车运输到筑波的健康食蟹猴和比格犬血清生化参数的变化。运输过程中，猴子血清皮质醇、总胆红素和天冬氨酸转氨酶的浓度升高。运输过程中，犬血清皮质醇和总胆红素水平也升高，但血清甘油三酯降低。用卡车运输的猴子和犬血清参数值在到达后两周内恢复到基线水平。综上所述，这些结果表明，两周的适应期是公路运输后适应所需的最短持续时间。
