Lee V R, Darney B G, Snowden J M, Main E K, Gilbert W, Chung J, Caughey A B
Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, OR, USA.
National Public Health Institute, Cuernvaca, Mexico.
BJOG. 2016 Jan;123(2):271-8. doi: 10.1111/1471-0528.13807.
To compare perinatal outcomes between elective induction of labour (eIOL) and expectant management in obese women.
Retrospective cohort study.
Deliveries in California in 2007.
Term, singleton, vertex, nonanomalous deliveries among obese women (n = 74 725).
Women who underwent eIOL at 37 weeks were compared with women who were expectantly managed at that gestational age. Similar comparisons were made at 38, 39, and 40 weeks. Results were stratified by parity. Chi-square tests and multivariable logistic regression were used for statistical comparison.
Method of delivery, severe perineal lacerations, postpartum haemorrhage, chorioamnionitis, macrosomia, shoulder dystocia, brachial plexus injury, respiratory distress syndrome.
The odds of caesarean delivery were lower among nulliparous women with eIOL at 37 weeks [odds ratio (OR) 0.55, 95% confidence interval (CI) 0.34-0.90] and 39 weeks (OR 0.77, 95% CI 0.63-0.95) compared to expectant management. Among multiparous women with a prior vaginal delivery, eIOL at 37 (OR 0.39, 95% CI 0.24-0.64), 38 (OR 0.65, 95% CI 0.51-0.82), and 39 weeks (OR 0.67, 95% CI 0.56-0.81) was associated with lower odds of caesarean. Additionally, eIOL at 38, 39, and 40 weeks was associated with lower odds of macrosomia. There were no differences in the odds of operative vaginal delivery, lacerations, brachial plexus injury or respiratory distress syndrome.
In obese women, term eIOL may decrease the risk of caesarean delivery, particularly in multiparas, without increasing the risks of other adverse outcomes when compared with expectant management.
比较肥胖女性择期引产(eIOL)与期待管理的围产期结局。
回顾性队列研究。
2007年加利福尼亚州的分娩情况。
肥胖女性中的足月、单胎、头位、无畸形分娩(n = 74725)。
将37周时接受eIOL的女性与该孕周接受期待管理的女性进行比较。在38、39和40周时进行类似比较。结果按产次分层。采用卡方检验和多变量逻辑回归进行统计学比较。
分娩方式、严重会阴裂伤、产后出血、绒毛膜羊膜炎、巨大儿、肩难产、臂丛神经损伤、呼吸窘迫综合征。
与期待管理相比,37周(比值比[OR] 0.55,95%置信区间[CI] 0.34 - 0.90)和39周(OR 0.77,95% CI 0.63 - 0.95)接受eIOL的初产妇剖宫产几率较低。在有阴道分娩史的经产妇中,37周(OR 0.39,95% CI 0.24 - 0.64)、38周(OR 0.65,95% CI 0.51 - 0.82)和39周(OR 0.67,95% CI 0.56 - 0.81)接受eIOL与较低的剖宫产几率相关。此外,38、39和40周接受eIOL与较低的巨大儿几率相关。手术阴道分娩、裂伤、臂丛神经损伤或呼吸窘迫综合征的几率无差异。
在肥胖女性中,足月eIOL与期待管理相比,可能降低剖宫产风险,尤其是经产妇,且不增加其他不良结局的风险。