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[通过血涂片淋巴细胞中琥珀酸脱氢酶活性评估近红外光对大鼠的影响]

[Effects of Light Near-Infrared Radiation on Rats Assessed by Succinate Dehydrogenase Activity in Lymphocytes on Blood Smears].

作者信息

Khunderyakova N V, Zakharchenko A V, Zakharchenko M V, Muller H, Fedotcheva I, Kondrashova M N

出版信息

Biofizika. 2015 Nov-Dec;60(6):1104-8.

PMID:26841503
Abstract

Biological effects of light near infrared radiation (850 nm), with modulation acoustic frequency of 101 Hz, was studied. The study was conducted on rats, the effect was recorded by succinate dehydrogenase activity in lymphocytes on the blood smear after administration of the activating dose of adrenaline, which simulates the state of the organism in the early stages of the pathogenic effects (stress). A pronounced regulating effect of infrared radiation on the activity of succinate dehydrogenase in animals activated by adrenaline was shown. Infrared radiation has a normalizing effect reducing the degree of inhibition or activation of the enzyme induced by adrenaline and had no effect on the control animals. Thus, by modulating the activity of succinate dehydrogenase infrared radiation regulates energy production in the mitochondria supported by the most powerful oxidation substrate--succinic acid, which is especially pronounced under stress.

摘要

研究了调制声频为101Hz的近红外辐射(850nm)的生物学效应。该研究以大鼠为对象,在给予模拟致病效应(应激)早期机体状态的激活剂量肾上腺素后,通过血液涂片上淋巴细胞中的琥珀酸脱氢酶活性来记录效应。结果显示,红外辐射对肾上腺素激活的动物体内琥珀酸脱氢酶的活性具有显著的调节作用。红外辐射具有归一化作用,可降低肾上腺素诱导的酶抑制或激活程度,且对对照动物无影响。因此,通过调节琥珀酸脱氢酶的活性,红外辐射可调节由最强有力的氧化底物——琥珀酸支持的线粒体中的能量产生,这在应激状态下尤为明显。

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Biofizika. 2015 Nov-Dec;60(6):1104-8.
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[Effect of adrenaline on the succinate dehydrogenase activity of peripheral blood lymphocytes of rats following exposure to ionizing radiation].[肾上腺素对电离辐射后大鼠外周血淋巴细胞琥珀酸脱氢酶活性的影响]
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