Feyzizarnagh Hamid, Yoon Do-Young, Goltz Mark, Kim Dong-Shik
Department of Chemical & Environmental Engineering, University of Toledo, Toledo, OH, USA.
Department of Chemical Engineering, Kwangwoon University, Seoul, Korea.
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2016 Sep;8(5):730-43. doi: 10.1002/wnan.1393. Epub 2016 Feb 5.
Nanostructures of peptides have been investigated for biomedical applications due to their unique mechanical and electrical properties in addition to their excellent biocompatibility. Peptides may form fibrils, spheres and tubes in nanoscale depending on the formation conditions. These peptide nanostructures can be used in electrical, medical, dental, and environmental applications. Applications of these nanostructures include, but are not limited to, electronic devices, biosensing, medical imaging and diagnosis, drug delivery, tissue engineering and stem cell research. This review offers a discussion of basic synthesis methods, properties and application of these nanomaterials. The review concludes with recommendations and future directions for peptide nanostructures. WIREs Nanomed Nanobiotechnol 2016, 8:730-743. doi: 10.1002/wnan.1393 For further resources related to this article, please visit the WIREs website.
由于其独特的机械和电学性质以及出色的生物相容性，肽的纳米结构已被研究用于生物医学应用。根据形成条件，肽可以在纳米尺度上形成纤维、球体和管状结构。这些肽纳米结构可用于电气、医学、牙科和环境应用。这些纳米结构的应用包括但不限于电子设备、生物传感、医学成像与诊断、药物递送、组织工程和干细胞研究。本文综述了这些纳米材料的基本合成方法、性质及应用。综述最后给出了肽纳米结构的建议和未来发展方向。《WIREs纳米医学与纳米生物技术》2016年，8:730 - 743。doi:10.1002/wnan.1393 有关本文的更多资源，请访问WIREs网站。
