Bock E, Keller F, Heitz J, Heinemeyer G
Freie Universität Berlin, Klinikum Steglitz, Department of Internal Medicine, FRG.
Int J Clin Pharmacol Ther Toxicol. 1989 Oct;27(10):490-2.
A severe carbamazepine intoxication in a 45-year-old woman was treated with combined hemodialysis/hemoperfusion. The ingested dose was estimated as 4-36 g. Serum carbamazepine levels were determined by fluorescence polarization immunoassay. The detoxication was performed 18 h after admission and resulted in a 50 percent reduction in serum drug levels accompanied by rapid clinical improvement.