Department of Nephrology, Ankara Education and Research Hospital, Ankara, Turkey.
Blood Purif. 2012;33(4):225-6. doi: 10.1159/000335608. Epub 2012 Jan 25.
Hemodialysis (HD) is a technique that helps in the management of drug intoxications/overdoses - the most important point being the protein-binding rate of the molecules which have to be cleared. In cases where the drug is not bound to the proteins, conventional HD may be effective enough, but if the drug is highly bound to proteins then HD may be insufficient to be effective. Hemoperfusion and albumin dialysis are therefore appropriate alternatives. Herein we report a case of carbamazepine intoxication where conventional HD treatment was performed.
血液透析（HD）是一种有助于药物中毒/过量管理的技术 - 最重要的是要清除的分子的蛋白结合率。在药物未与蛋白质结合的情况下，常规 HD 可能已经足够有效，但如果药物与蛋白质高度结合，则 HD 可能不足以有效。因此，血液灌流和白蛋白透析是合适的替代方法。在此，我们报告了一例卡马西平中毒的病例，其中进行了常规 HD 治疗。
