Principi Nicola, Marchisio Paola, Esposito Susanna
a Pediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation , Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico , Milan , Italy.
Expert Rev Anti Infect Ther. 2016;14(4):415-23. doi: 10.1586/14787210.2016.1150781. Epub 2016 Feb 26.
Otitis media with effusion (OME) is a common clinical condition that is associated with hearing loss. It can be diagnosed at least once in approximately 80% of preschool children: 30-40% of them have recurrent episodes, and 5-10% have chronic disease. OME, in recurrent and persistent cases, might significantly delay or impair communication skills, resulting in behavioral and educational difficulties. Several therapeutic approaches have been used to avoid these problems. Most, however, have not been adequately studied, and no definitive conclusions can be drawn. Official guidelines do not recommend the use of decongestants, antihistamines, steroids, or antibiotics. The data are too scanty to assess other interventions, although autoinflation, because it incurs neither cost nor adverse events, deserves attention. Surgical procedures (i.e., tympanostomy tube insertion and adenoidectomy as an adjuvant) can be useful in some cases. This review evaluates all the current OME treatments and preventive measures, including their possible adverse events.
分泌性中耳炎(OME)是一种与听力损失相关的常见临床病症。大约80%的学龄前儿童至少会被诊断出一次OME:其中30 - 40%会复发,5 - 10%患有慢性病。在复发和持续的病例中,OME可能会显著延迟或损害沟通能力,导致行为和教育方面的困难。已经采用了几种治疗方法来避免这些问题。然而,大多数方法尚未得到充分研究,无法得出明确结论。官方指南不建议使用减充血剂、抗组胺药、类固醇或抗生素。虽然自行鼓气法由于既无成本又无不良事件,值得关注,但评估其他干预措施的数据过于稀少。手术程序(即鼓膜置管和腺样体切除术作为辅助手术)在某些情况下可能有用。本综述评估了当前所有的OME治疗方法和预防措施,包括它们可能的不良事件。