Yoon Jin H, Park Yongbum, Ahn Jaeki, Shin Kyung A, Kim Young J
Department of Sport and Leisure Studies, Far East University, Chungbuk, Korea -
J Sports Med Phys Fitness. 2016 Mar;56(3):295-301. Epub 2016 Jan 22.
The aim of this study was to compare pre- and postcompetition markers of cardiac damage in ultraendurance athletes.
All the subjects had blood samples collected before starting and immediately after completing the running race, in order to analyze CK, hs-CRP, cTnI, and NT-proBNP.
Before starting the marathon, there were no differences between the groups for all of the tests. CK was significantly higher after the 308 km ultra-marathon than after the marathon and the 100 km ultra-marathon (P<0.001). In cTnI, the value after the 100 km ultra-marathon was significantly higher than that after the marathon and 308 km ultra-marathon, respectively (P<0.05, P<0.01). NT-proBNP was significantly higher after the 100 km and 308 km ultra-marathons than after the marathon (P<0.01, P<0.01). Hs-CRP was significantly higher after the 308 km ultra-marathon than after the marathon and the 100 km ultra-marathon (P<0.001).
cTnI was expressed after marathon and the 100 km ultra-marathon, and NT-proBNP exceeding the upper reference limit (URL) was expressed in long-distance races such as the 100 km and 308 km ultra-marathons. The highest expression of cTnI and NT-proBNP exceeding the URL was in the 100 km ultra-marathon, which may be caused by a combination of the moderate intensity of the exercise and the long-running distance.
本研究的目的是比较超耐力运动员比赛前后心脏损伤的标志物。
所有受试者在起跑前和跑完比赛后立即采集血样，以分析肌酸激酶（CK）、高敏C反应蛋白（hs-CRP）、心肌肌钙蛋白I（cTnI）和N末端脑钠肽前体（NT-proBNP）。
在马拉松比赛开始前，所有测试组之间均无差异。308公里超级马拉松赛后的CK显著高于马拉松赛后和100公里超级马拉松赛后（P<0.001）。在cTnI方面，100公里超级马拉松赛后的值分别显著高于马拉松赛后和308公里超级马拉松赛后（P<0.05，P<0.01）。100公里和308公里超级马拉松赛后的NT-proBNP显著高于马拉松赛后（P<0.01，P<0.01）。308公里超级马拉松赛后的hs-CRP显著高于马拉松赛后和100公里超级马拉松赛后（P<0.001）。
马拉松赛后和100公里超级马拉松赛后可检测到cTnI，而在100公里和308公里超级马拉松等长跑比赛中可检测到NT-proBNP超过参考上限（URL）。cTnI和NT-proBNP超过URL的最高表达出现在100公里超级马拉松赛中，这可能是由中等强度的运动和较长的跑步距离共同导致的。
