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TOR (target of rapamycin) is a key regulator of triacylglycerol accumulation in microalgae.雷帕霉素靶蛋白（TOR）是微藻中三酰甘油积累的关键调节因子。
Plant Signal Behav. 2016;11(3):e1149285. doi: 10.1080/15592324.2016.1149285.
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Target of rapamycin (TOR) plays a critical role in triacylglycerol accumulation in microalgae.雷帕霉素靶蛋白（TOR）在微藻三酰基甘油积累中发挥着关键作用。
Plant Mol Biol. 2015 Oct;89(3):309-18. doi: 10.1007/s11103-015-0370-6. Epub 2015 Sep 8.
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Microalgal Target of Rapamycin (TOR): A Central Regulatory Hub for Growth, Stress Response and Biomass Production.微藻雷帕霉素靶蛋白（TOR）：生长、应激反应和生物量生产的中央调控中心。
Plant Cell Physiol. 2020 Apr 1;61(4):675-684. doi: 10.1093/pcp/pcaa023.
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Investigating the effect of target of rapamycin kinase inhibition on the Chlamydomonas reinhardtii phosphoproteome: from known homologs to new targets.研究雷帕霉素靶蛋白激酶抑制对莱茵衣藻磷酸蛋白质组的影响：从已知同源物到新靶标。
New Phytol. 2019 Jan;221(1):247-260. doi: 10.1111/nph.15339. Epub 2018 Jul 24.
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Inhibition of TOR in Leads to Rapid Cysteine Oxidation Reflecting Sustained Physiological Changes.雷帕霉素靶蛋白（TOR）的抑制导致迅速的半胱氨酸氧化，反映出持续的生理变化。
Cells. 2019 Sep 28;8(10):1171. doi: 10.3390/cells8101171.
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Targeting TOR signaling for enhanced lipid productivity in algae.靶向 TOR 信号通路提高藻类的油脂产量。
Biochimie. 2020 Feb;169:12-17. doi: 10.1016/j.biochi.2019.06.016. Epub 2019 Jun 29.
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Nitrogen starvation leads to TOR kinase-mediated downregulation of fatty acid synthesis in the algae Chlorella sorokiniana and Chlamydomonas reinhardtii.氮饥饿导致藻类集胞藻和莱茵衣藻中的 TOR 激酶介导的脂肪酸合成下调。
BMC Plant Biol. 2024 Aug 6;24(1):753. doi: 10.1186/s12870-024-05408-7.
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Inhibition of target of rapamycin signaling by rapamycin in the unicellular green alga Chlamydomonas reinhardtii.雷帕霉素对单细胞绿藻莱茵衣藻中雷帕霉素靶蛋白信号通路的抑制作用。
Plant Physiol. 2005 Dec;139(4):1736-49. doi: 10.1104/pp.105.070847. Epub 2005 Nov 18.
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Functional analysis of three type-2 DGAT homologue genes for triacylglycerol production in the green microalga Chlamydomonas reinhardtii.三种 2 型 DGAT 同源基因在绿藻莱茵衣藻中用于三酰基甘油生产的功能分析。
J Biotechnol. 2012 Nov 30;162(1):13-20. doi: 10.1016/j.jbiotec.2012.04.006. Epub 2012 Apr 20.
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Overexpression of a Transcription Factor Enhances Triacylglycerol and Starch Accumulation and Biomass Production in the Green Microalga .转录因子过表达增强了绿色微藻中的三酰基甘油和淀粉积累及生物量生产。
J Agric Food Chem. 2023 Nov 22;71(46):17833-17841. doi: 10.1021/acs.jafc.3c05290. Epub 2023 Nov 7.
引用本文的文献
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Light-dark dependent changes in chloroplast and mitochondrial activity in .（植物）中叶绿体和线粒体活性的光暗依赖性变化 。
注：原文中“in.”后面应该还有具体的研究对象等相关内容，这里按照完整句子理解进行了补充翻译。仅根据现有原文翻译会稍显突兀。
Front Plant Sci. 2025 Jul 17;16:1622214. doi: 10.3389/fpls.2025.1622214. eCollection 2025.
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Target of Rapamycin is a crucial regulator of photosynthesis and nutrient metabolism partitioning in Nannochloropsis gaditana.雷帕霉素靶蛋白是杜氏盐藻光合作用和营养物质代谢分配的关键调节因子。
Biotechnol Biofuels Bioprod. 2025 Feb 22;18(1):21. doi: 10.1186/s13068-025-02617-6.
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NgLst8 Coactivates TOR Signaling to Activate Photosynthetic Growth in .NgLst8 共激活 TOR 信号传导以激活光合作用生长 。 （原文句子不完整，此为按现有内容翻译）
Microorganisms. 2024 Dec 13;12(12):2574. doi: 10.3390/microorganisms12122574.
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Nitrogen starvation leads to TOR kinase-mediated downregulation of fatty acid synthesis in the algae Chlorella sorokiniana and Chlamydomonas reinhardtii.氮饥饿导致藻类集胞藻和莱茵衣藻中的 TOR 激酶介导的脂肪酸合成下调。
BMC Plant Biol. 2024 Aug 6;24(1):753. doi: 10.1186/s12870-024-05408-7.
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GATA-type transcriptional factor SpGAT1 interacts with SpMIG1 and promotes lipid accumulation in the oleaginous yeast zwy-2-3.GATA型转录因子SpGAT1与SpMIG1相互作用并促进产油酵母zwy-2-3中的脂质积累。
Biotechnol Biofuels Bioprod. 2022 Oct 8;15(1):103. doi: 10.1186/s13068-022-02177-z.
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Target of Rapamycin Signaling Involved in the Regulation of Photosynthesis and Cellular Metabolism in .雷帕霉素靶蛋白信号参与. 中的光合作用和细胞代谢的调节。
Int J Mol Sci. 2022 Jul 4;23(13):7451. doi: 10.3390/ijms23137451.
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Deciphering the function and evolution of the target of rapamycin signaling pathway in microalgae.解析微藻雷帕霉素靶蛋白信号通路的功能和进化。
J Exp Bot. 2022 Nov 15;73(20):6993-7005. doi: 10.1093/jxb/erac264.
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Amino Acid Signaling for TOR in Eukaryotes: Sensors, Transducers, and a Sustainable Agricultural fuTORe.真核生物中 TOR 的氨基酸信号：传感器、转导器和可持续农业的未来。
Biomolecules. 2022 Mar 2;12(3):387. doi: 10.3390/biom12030387.
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Role of Autophagy in Cell Growth under Salinity.自噬在盐胁迫下细胞生长中的作用。
Plants (Basel). 2022 Jan 12;11(2):197. doi: 10.3390/plants11020197.
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The Unicellular Red Alga , an Excellent Model Organism for Elucidating Fundamental Molecular Mechanisms and Their Applications in Biofuel Production.单细胞红藻，一种用于阐明基本分子机制及其在生物燃料生产中应用的优秀模式生物。
Plants (Basel). 2021 Jun 15;10(6):1218. doi: 10.3390/plants10061218.
本文引用的文献
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Expression profiling and functional analysis reveals that TOR is a key player in regulating photosynthesis and phytohormone signaling pathways in Arabidopsis.表达谱分析和功能分析表明，TOR是调节拟南芥光合作用和植物激素信号通路的关键因子。
Front Plant Sci. 2015 Sep 7;6:677. doi: 10.3389/fpls.2015.00677. eCollection 2015.
2
Target of rapamycin (TOR) plays a critical role in triacylglycerol accumulation in microalgae.雷帕霉素靶蛋白（TOR）在微藻三酰基甘油积累中发挥着关键作用。
Plant Mol Biol. 2015 Oct;89(3):309-18. doi: 10.1007/s11103-015-0370-6. Epub 2015 Sep 8.
3
Enhancement of extraplastidic oil synthesis in Chlamydomonas reinhardtii using a type-2 diacylglycerol acyltransferase with a phosphorus starvation-inducible promoter.利用具有磷饥饿诱导型启动子的2型二酰基甘油酰基转移酶增强莱茵衣藻质体外油脂合成
Plant Biotechnol J. 2014 Aug;12(6):808-19. doi: 10.1111/pbi.12210. Epub 2014 Jun 9.
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Expression of budding yeast FKBP12 confers rapamycin susceptibility to the unicellular red alga Cyanidioschyzon merolae.表达酿酒酵母 FKBP12 使单细胞红藻 Cyanidioschyzon merolae 对雷帕霉素敏感。
Biochem Biophys Res Commun. 2013 Sep 20;439(2):264-9. doi: 10.1016/j.bbrc.2013.08.045. Epub 2013 Aug 22.
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Glucose-TOR signalling reprograms the transcriptome and activates meristems.葡萄糖-TOR 信号重新编程转录组并激活分生组织。
Nature. 2013 Apr 11;496(7444):181-6. doi: 10.1038/nature12030. Epub 2013 Mar 31.
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A galactoglycerolipid lipase is required for triacylglycerol accumulation and survival following nitrogen deprivation in Chlamydomonas reinhardtii.半乳糖甘油酯脂肪酶在莱茵衣藻氮饥饿后三酰基甘油积累和存活中是必需的。
Plant Cell. 2012 Nov;24(11):4670-86. doi: 10.1105/tpc.112.105106. Epub 2012 Nov 16.
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Three acyltransferases and nitrogen-responsive regulator are implicated in nitrogen starvation-induced triacylglycerol accumulation in Chlamydomonas.三种酰基转移酶和氮响应调节剂参与了氮饥饿诱导的衣藻三酰基甘油积累。
J Biol Chem. 2012 May 4;287(19):15811-25. doi: 10.1074/jbc.M111.334052. Epub 2012 Mar 8.
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Rapamycin passes the torch: a new generation of mTOR inhibitors.雷帕霉素传递火炬：新一代 mTOR 抑制剂。
Nat Rev Drug Discov. 2011 Oct 31;10(11):868-80. doi: 10.1038/nrd3531.
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Aquatic phototrophs: efficient alternatives to land-based crops for biofuels.水生光合生物：用于生物燃料的陆地作物的高效替代品。
Curr Opin Biotechnol. 2008 Jun;19(3):235-40. doi: 10.1016/j.copbio.2008.05.007. Epub 2008 Jun 6.
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Biodiesel from microalgae beats bioethanol.微藻生物柴油优于生物乙醇。
Trends Biotechnol. 2008 Mar;26(3):126-31. doi: 10.1016/j.tibtech.2007.12.002. Epub 2008 Jan 24.
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