Department of Ophthalmology, Advanced Eye Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.
Indian J Pediatr. 2017 Dec;84(12):930-936. doi: 10.1007/s12098-017-2404-3. Epub 2017 Jul 4.
Retinopathy of prematurity (ROP) is a proliferative retinal vascular disease affecting the retina of premature infants. The clinical spectrum of ROP varies from spontaneous regression to bilateral retinal detachment and total blindness. Between these two extremes lies the form of ROP, which is amenable to treatment with laser photocoagulation, anti-vascular endothelial growth factor drugs or surgery. Increasing rates of preterm births coupled with better survival rates but lack of uniform quality of neonatal care and delays in diagnosis have led to increasing ROP blindness. Atypical forms of Aggressive Posterior ROP are seen in heavier birth weight babies in developing countries. Prevention of ROP by following stringent protocols for supplemental oxygen, prevention of sepsis, timely screening and laser treatment by a concerted and collaborative effort of neonatologists and ophthalmologists are required to fight the blindness from ROP.
早产儿视网膜病变（ROP）是一种影响早产儿视网膜的增生性视网膜血管疾病。ROP 的临床谱从自发消退到双眼视网膜脱离和完全失明不等。在这两个极端之间，ROP 的形式是可以通过激光光凝、抗血管内皮生长因子药物或手术治疗的。早产儿出生率的增加，加上更好的存活率，但缺乏统一的新生儿护理质量和诊断延迟，导致 ROP 失明的增加。在发展中国家，较重出生体重的婴儿中出现了非典型的侵袭性后部 ROP。需要通过新生儿科医生和眼科医生的共同努力，严格遵循补充氧气、预防败血症、及时筛查和激光治疗的方案来预防 ROP，以对抗 ROP 导致的失明。
