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生命状态与癌症

The living state and cancer.

作者信息

Szent-Györgyi A

出版信息

Proc Natl Acad Sci U S A. 1977 Jul;74(7):2844-7. doi: 10.1073/pnas.74.7.2844.

DOI:10.1073/pnas.74.7.2844
PMID:268635
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC431314/
Abstract

Complex living structures developed on our globe after the appearance of light and oxygen. In functions of these structures, solid state phenomena play a major role. The structural proteins were made into radicals by doping, the covalent incorporation of electron acceptors. This lent mobility to their electrons and a subtle reactivity to their molecules. Cancer is unable to go into the radical state.

摘要

在光和氧气出现之后,复杂的生命结构在我们的地球上发展起来。在这些结构的功能中,固态现象起着主要作用。通过掺杂(电子受体的共价掺入),结构蛋白被转化为自由基。这赋予了它们电子的流动性以及分子的微妙反应性。癌症无法进入自由基状态。

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The living state and cancer.生命状态与癌症
Proc Natl Acad Sci U S A. 1977 Jul;74(7):2844-7. doi: 10.1073/pnas.74.7.2844.
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本文引用的文献

1
Cell division, SH, ketoaldehydes, and cancer.细胞分裂、SH、酮醛与癌症。
Proc Natl Acad Sci U S A. 1966 Feb;55(2):388-93. doi: 10.1073/pnas.55.2.388.
2
Dietary enhancement of intestinal carcinogenesis by dimethylhydrazine in rats.
Nature. 1973;246(5434):491-2. doi: 10.1038/246491a0.
3
Electron spin resonance absorption of tissue constituents.组织成分的电子自旋共振吸收
Proc Natl Acad Sci U S A. 1977 Apr;74(4):1558-60. doi: 10.1073/pnas.74.4.1558.
4
Electronic properties of the casein-methylglyoxal complex.酪蛋白-甲基乙二醛复合物的电子特性。
Proc Natl Acad Sci U S A. 1977 Jan;74(1):226-8. doi: 10.1073/pnas.74.1.226.