Corrales C Eduardo, Bhattacharyya Neil
Division of Otolaryngology-Head and Neck Surgery, Brigham and Women's Hospital, Harvard Medical School, and Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts, U.S.A.
Laryngoscope. 2016 Sep;126(9):2134-6. doi: 10.1002/lary.25902. Epub 2016 Feb 10.
OBJECTIVES/HYPOTHESIS: To determine if dizziness is an independent risk factor for mortality among adults in the United States.
Cross-sectional analysis using the National Health Interview Survey (NHIS).
Adult respondents in the 2008 NHIS were evaluated. Demographic information (gender, race, ethnicity, education level), prevalence of dizziness, mortality rates, and leading causes of death (cardiovascular disease, cancer, diabetes, cerebrovascular disease) were collected and analyzed. The association between dizziness and subsequent mortality was determined adjusting for demographic and other disease factors.
Among 213.6 ± 3.5 million adult Americans, 23.8 ± 0.7 million reported dizziness in the past 12 months (11.1% ± 0.3%; mean age, 45.9 ± 0.2 years; 51.7% ± 0.5% female). The mortality rate among the group without dizziness in the preceding 12 months was 2.6% ± 0.1%, compared to the dizzy group at 9.0% ± 0.7%. After adjusting for gender and age, there was a statistically significant association between dizziness and mortality (odds ratio [OR]: 2.2, 95% confidence interval [CI]: 1.8-2.8). After adjusting for all covariates including age, ethnicity, race, gender, diabetes, cardiovascular, cerebrovascular disease, cancer, and grade level, dizziness remained an independent predictor of increased mortality (adjusted OR: 1.7, 95% CI: 1.36-2.18).
Approximately 11% of adult Americans reported dizziness or balance problems in the preceding 12 months. Adults with dizziness have a greater mortality rate than nondizzy adults. Even after adjusting for covariates, there was a significant association between dizziness and mortality. Screening for dizziness as a risk factor for mortality may be warranted.
2b Laryngoscope, 126:2134-2136, 2016.
目的/假设：确定头晕是否为美国成年人死亡的独立危险因素。
采用美国国家健康访谈调查（NHIS）进行横断面分析。
对2008年NHIS中的成年受访者进行评估。收集并分析人口统计学信息（性别、种族、民族、教育水平）、头晕患病率、死亡率以及主要死因（心血管疾病、癌症、糖尿病、脑血管疾病）。在对人口统计学和其他疾病因素进行校正后，确定头晕与后续死亡率之间的关联。
在2.136±0.035亿成年美国人中，有2380±70万报告在过去12个月内有头晕症状（11.1%±0.3%；平均年龄45.9±0.2岁；女性占51.7%±0.5%）。在之前12个月内无头晕症状的人群死亡率为2.6%±0.1%，而头晕人群的死亡率为9.0%±0.7%。在对性别和年龄进行校正后，头晕与死亡率之间存在统计学显著关联（优势比[OR]：2.2，95%置信区间[CI]：1.8 - 2.8）。在对包括年龄、民族、种族、性别、糖尿病、心血管疾病、脑血管疾病、癌症和教育水平在内的所有协变量进行校正后，头晕仍然是死亡率增加的独立预测因素（校正后OR：1.7，95%CI：1.36 - 2.18）。
约11%的成年美国人报告在过去12个月内有头晕或平衡问题。有头晕症状的成年人死亡率高于无头晕症状的成年人。即使在对协变量进行校正后，头晕与死亡率之间仍存在显著关联。对头晕作为死亡危险因素进行筛查可能是有必要的。
2b 《喉镜》，126:2134 - 2136，2016年。
