Brickell P M, Tickle C
Bioessays. 1989 Nov;11(5):145-9. doi: 10.1002/bies.950110508.
Retinoic acid is a good candidate for a morphogen in chick limb bud development. The challenge now is to determine how retinoic acid interacts with limb bud cells and how the retinoic acid signal is integrated with other signals to mould and pattern the developing limb.
视黄酸是鸡胚肢体芽发育中形态发生素的一个良好候选物。现在面临的挑战是确定视黄酸如何与肢体芽细胞相互作用,以及视黄酸信号如何与其他信号整合,从而塑造和规划发育中的肢体。