Cuny Christiane, Witte Wolfgang
Robert Koch Institute, Wernigerode Branch Burgstrasse, 3738855 Wernigerode, Germany.
Robert Koch Institute, Wernigerode Branch Burgstrasse, 3738855 Wernigerode, Germany.
Vet Microbiol. 2017 Feb;200:59-64. doi: 10.1016/j.vetmic.2016.01.013. Epub 2016 Jan 21.
MRSA infections in equine clinics were reported from Northern America, Europe, Australia, and Japan. The majority of nosocomial infections in horses is obviously associated with particular MRSA clonal lineages. As already observed for epidemic MRSA in human hospitals more than 10 years ago, a dynamics of MRSA clonal lineages is also observed in European equine clinics: clonal lineages belonging to clonal complex (CC) 8 are on the retreat whereas MRSA attributed to CC398 become increasingly prevalent. The majority of CC398 isolates belong to a subpopulation which is particularly associated with equine hospitals as indicated by molecular typing. When emerging in equine clinics, MRSA from horses were also found as nasal colonizers of veterinary personnel. MRSA exhibiting the typing characteristics of MRSA known from equine clinics are obviously rare among MRSA from infections in humans. Although rare so far epidemic MRSA from human hospitals (HA-MRSA, e.g., ST22, ST225) have been isolated from nosocomial infections in horses and need particular attention in further surveillance.
北美、欧洲、澳大利亚和日本均有关于马医院耐甲氧西林金黄色葡萄球菌（MRSA）感染的报道。马医院内的大多数医院感染显然与特定的MRSA克隆谱系有关。正如10多年前在人类医院中观察到的流行MRSA一样，在欧洲马医院也观察到了MRSA克隆谱系的动态变化：属于克隆复合体（CC）8的克隆谱系正在减少，而归因于CC398的MRSA变得越来越普遍。分子分型表明，大多数CC398分离株属于一个特别与马医院相关的亚群。当MRSA在马医院出现时，来自马的MRSA也被发现是兽医人员鼻腔的定植菌。在人类感染的MRSA中，表现出马医院已知的MRSA分型特征的MRSA显然很少见。尽管迄今为止很少见，但已从马的医院感染中分离出人类医院的流行MRSA（医院获得性MRSA，例如ST22、ST225），在进一步监测中需要特别关注。
