Schlenz Alyssa M, Schatz Jeffrey, Roberts Carla W
Department of Psychology, University of South Carolina, Department of Pediatrics, Medical University of South Carolina, and
Department of Psychology, University of South Carolina.
J Pediatr Psychol. 2016 Sep;41(8):930-40. doi: 10.1093/jpepsy/jsw003. Epub 2016 Feb 10.
To examine biopsychosocial variables in relation to multiple pain features in pediatric sickle cell disease (SCD).
76 children with SCD (M = 14.05, SD = 3.26), ages 8-19 years, and 70 caregivers completed measures of coping, mood, and family functioning and reported on multiple pain features via retrospective interviews during routine hematological visits. Sickle cell genotype and health care utilization were collected via medical record review. Using hierarchical regression, biological (genotype), child psychological (coping and mood), and social factors (caregiver coping and family functioning) were evaluated in relation to multiple pain features.
Genotype was associated with pain intensity, and child psychological factors were associated with pain frequency. Multiple biopsychosocial factors were related to health care utilization.
Biopsychosocial factors may have distinct relationships with pain features in pediatric SCD. Understanding these relationships may refine the biopsychosocial model and inform integrated medical and psychosocial approaches in SCD.
研究儿童镰状细胞病（SCD）中生物心理社会变量与多种疼痛特征之间的关系。
76名年龄在8至19岁之间的SCD儿童（M = 14.05，标准差 = 3.26）以及70名照料者完成了应对、情绪和家庭功能的测量，并在常规血液学检查期间通过回顾性访谈报告了多种疼痛特征。通过病历审查收集镰状细胞基因型和医疗保健利用情况。使用分层回归分析，评估了生物因素（基因型）、儿童心理因素（应对和情绪）以及社会因素（照料者应对和家庭功能）与多种疼痛特征之间的关系。
基因型与疼痛强度相关，儿童心理因素与疼痛频率相关。多种生物心理社会因素与医疗保健利用情况有关。
生物心理社会因素可能与儿童SCD的疼痛特征存在不同的关系。了解这些关系可能会完善生物心理社会模型，并为SCD的综合医学和心理社会治疗方法提供依据。
