Levin S, Yurgelun-Todd D, Craft S
J Abnorm Psychol. 1989 Nov;98(4):341-56. doi: 10.1037//0021-843x.98.4.341.
Clinical neuropsychological findings are examined with respect to competing hypotheses about localized neuropathology in schizophrenia. Two general models of structural and functional impairment are described. The first addresses deficits in cortical/subcortical processes concerned with arousal, attention, and higher cortical functions. The second addresses impairments in the balance of lateralized functions consistent with left hemisphere overactivation. Empirical data provide support for both models, and suggest that the explanatory power of these models may vary when they are applied to different subtypes of schizophrenia.
针对精神分裂症局部神经病理学的相互竞争假说，对临床神经心理学研究结果进行了考察。描述了两种结构和功能损伤的一般模型。第一种模型涉及与觉醒、注意力和高级皮层功能相关的皮质/皮质下过程中的缺陷。第二种模型涉及与左半球过度激活相一致的功能偏侧化平衡受损。实证数据为这两种模型都提供了支持，并表明当这些模型应用于不同亚型的精神分裂症时，其解释力可能会有所不同。
