Tang Shou-Jiang, Vilmann Andreas S, Saftoiu Adrian, Wang Wanmei, Streba Costin Teodor, Fink Peter P, Griswold Michael, Wu Ruonan, Dietrich Christoph F, Jenssen Christian, Hocke Michael, Kantowski Marcus, Pohl Jürgen, Fockens Paul, Annema Jouke T, van der Heijden Erik H F M, Havre Roald Flesland, Pham Khanh Do-Cong, Kunda Rastislav, Deprez Pierre H, Mariana Jinga, Vazquez-Sequeiros Enrique, Larghi Alberto, Buscarini Elisabetta, Fusaroli Pietro, Lahav Maor, Puri Rajesh, Garg Pramod Kumar, Sharma Malay, Maluf-Filho Fauze, Sahai Anand, Brugge William R, Lee Linda S, Aslanian Harry R, Wang Andrew Y, Shami Vanessa M, Markowitz Arnold, Siddiqui Ali A, Mishra Girish, Scheiman James M, Isenberg Gerard, Siddiqui Uzma D, Shah Raj J, Buxbaum James, Watson Rabindra R, Willingham Field F, Bhutani Manoop S, Levy Michael J, Harris Cynthia, Wallace Michael B, Nolsøe Christian Pállson, Lorentzen Torben, Bang Niels, Sørensen Sten Mellerup, Gilja Odd Helge, D'Onofrio Mirko, Piscaglia Fabio, Gritzmann Norbert, Radzina Maija, Sparchez Zeno Adrian, Sidhu Paul S, Freeman Simon, McCowan Timothy C, de Araujo Cyrillo Rodrigues, Patel Akash, Ali Mohammad Adel, Campbell Garth, Chen Edward, Vilmann Peter
Division of Digestive Diseases, Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, USA.
GastroUnit, Copenhagen University Hospital Herlev, Copenhagen, Denmark.
Gastrointest Endosc. 2016 Sep;84(3):424-433.e2. doi: 10.1016/j.gie.2016.01.068. Epub 2016 Feb 10.
EUS-guided FNA or biopsy sampling is widely practiced. Optimal sonographic visualization of the needle is critical for image-guided interventions. Of the several commercially available needles, bench-top testing and direct comparison of these needles have not been done to reveal their inherent echogenicity. The aims are to provide bench-top data that can be used to guide clinical applications and to promote future device research and development.
Descriptive bench-top testing and comparison of 8 commonly used EUS-FNA needles (all size 22 gauge): SonoTip Pro Control (Medi-Globe); Expect Slimline (Boston Scientific); EchoTip, EchoTip Ultra, EchoTip ProCore High Definition (Cook Medical); ClearView (Conmed); EZ Shot 2 (Olympus); and BNX (Beacon Endoscopic), and 2 new prototype needles, SonoCoat (Medi-Globe), coated by echogenic polymers made by Encapson. Blinded evaluation of standardized and unedited videos by 43 EUS endoscopists and 17 radiologists specialized in GI US examination who were unfamiliar with EUS needle devices.
There was no significant difference in the ratings and rankings of these needles between endosonographers and radiologists. Overall, 1 prototype needle was rated as the best, ranking 10% to 40% higher than all other needles (P < .01). Among the commercially available needles, the EchoTip Ultra needle and the ClearView needle were top choices. The EZ Shot 2 needle was ranked statistically lower than other needles (30%-75% worse, P < .001).
All FNA needles have their inherent and different echogenicities, and these differences are similarly recognized by EUS endoscopists and radiologists. Needles with polymeric coating from the entire shaft to the needle tip may offer better echogenicity.
超声内镜引导下细针穿刺抽吸术（EUS-FNA）或活检采样应用广泛。针的最佳超声可视化对于图像引导介入至关重要。在几种市售针中，尚未进行台式测试及直接比较以揭示其固有回声性。目的是提供可用于指导临床应用的数据，并推动未来设备研发。
对8种常用的EUS-FNA针（均为22号）进行描述性台式测试及比较：SonoTip Pro Control（Medi-Globe公司）；Expect Slimline（波士顿科学公司）；EchoTip、EchoTip Ultra、EchoTip ProCore高清（库克医疗公司）；ClearView（康美公司）；EZ Shot 2（奥林巴斯公司）；以及BNX（Beacon Endoscopic公司），还有2种新型原型针SonoCoat（Medi-Globe公司），其由Encapson公司生产的回声聚合物涂层。由43名超声内镜医师和17名专门从事胃肠超声检查且不熟悉EUS针设备的放射科医师对标准化且未经编辑的视频进行盲法评估。
内镜超声医师和放射科医师对这些针的评分和排名无显著差异。总体而言，1种原型针被评为最佳，排名比所有其他针高10%至40%（P <.01）。在市售针中，EchoTip Ultra针和ClearView针是首选。EZ Shot 2针在统计学上排名低于其他针（差30% - 75%，P <.001）。
所有FNA针都有其固有的不同回声性，超声内镜医师和放射科医师对这些差异的认识相似。从整个针杆到针尖都有聚合物涂层的针可能具有更好的回声性。
