Yoshida Tetsuro, Kuwabara Mitsuo, Hoshide Satoshi, Kario Kazuomi
Department of Cardiovascular of Medicine, Onga Nakama Medical Association, Onga Hospital, Fukuoka, Japan.
Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan; Department of Sleep and Circadian Cardiology, Jichi Medical University School of Medicine, Tochigi, Japan.
J Am Soc Hypertens. 2016 Mar;10(3):201-4. doi: 10.1016/j.jash.2016.01.013. Epub 2016 Jan 25.
Obstructive sleep apnea syndrome (OSAS) causes resistant hypertension and a hypopnea-related nocturnal blood pressure (BP) surge. This could lead to an increase of not only the nocturnal BP level but also nocturnal BP variability, both of which increase an individual's cardiovascular risk. We recently developed a trigger sleep BP monitoring method that initiates BP measurement when an individual's oxygen desaturation falls below a variable threshold, and we demonstrated that it can detect a BP surge during apnea episodes. We here report the case of a 36-year-old man with severe OSAS who experienced the recurrence of stroke due to nocturnal hypoxia and a nocturnal BP surge measured by this trigger sleep BP monitoring device. A nocturnal BP surge during sleep in OSAS patients could be a strong trigger of cardiovascular events.
阻塞性睡眠呼吸暂停综合征（OSAS）可导致顽固性高血压以及与呼吸浅慢相关的夜间血压（BP）激增。这不仅会导致夜间血压水平升高，还会导致夜间血压变异性增加，而这两者都会增加个体的心血管风险。我们最近开发了一种触发式睡眠血压监测方法，当个体的氧饱和度降至可变阈值以下时启动血压测量，并且我们证明该方法能够检测呼吸暂停发作期间的血压激增。我们在此报告一例36岁重度OSAS男性患者，其因夜间低氧和通过这种触发式睡眠血压监测设备测得的夜间血压激增而出现中风复发。OSAS患者睡眠期间的夜间血压激增可能是心血管事件的强烈触发因素。
