Zhang Yu-Feng, Deng Hui-Ling, Fu Jia, Zhang Yu, Wei Jian-Qiang
Yu-Feng Zhang, Hui-Ling Deng, Jia Fu, Yu Zhang, Department Second of Infectious Diseases, Xi'an Children's Hospital, Xi'an 710003, Shaanxi Province, China.
World J Gastroenterol. 2016 Feb 14;22(6):2149-52. doi: 10.3748/wjg.v22.i6.2149.
Some viruses, including certain members of the enterovirus genus, have been reported to cause pancreatitis, especially Coxsackie virus. However, no case of human enterovirus 71 (EV71) associated with pancreatitis has been reported so far. We here report a case of EV71-induced hand-foot-and-mouth disease (HFMD) presenting with pancreatitis in a 2-year-old girl. This is the first report of a patient with acute pancreatitis in HFMD caused by EV71. We treated the patient conservatively with nasogastric suction, intravenous fluid and antivirals. The patient's symptoms improved after 8 d, and recovered without complications. We conclude that EV71 can cause acute pancreatitis in HFMD, which should be considered in differential diagnosis, especially in cases of idiopathic pancreatitis.
据报道，一些病毒，包括肠道病毒属的某些成员，可引起胰腺炎，尤其是柯萨奇病毒。然而，迄今为止，尚无人类肠道病毒71型（EV71）相关性胰腺炎的病例报告。我们在此报告1例2岁女童因EV71感染引起手足口病（HFMD）并伴有胰腺炎。这是首例由EV71引起的手足口病并发急性胰腺炎的病例报告。我们对该患者采用鼻胃管抽吸、静脉输液及抗病毒药物进行保守治疗。8天后患者症状改善，未出现并发症而康复。我们得出结论，EV71可导致手足口病并发急性胰腺炎，在鉴别诊断时应予以考虑，尤其是在特发性胰腺炎病例中。
