Lee Dae Yeong, Lorach Henri, Huie Phil, Palanker Daniel
Ophthalmic Surg Lasers Imaging Retina. 2016 Feb;47(2):171-4. doi: 10.3928/23258160-20160126-11.
Establish the surgical procedure for subretinal implantation of multiple photovoltaic arrays for the restoration of sight.
Multiple silicon photovoltaic arrays of 1 mm in diameter and 30 µm in thickness were implanted subretinally via single retinotomy in rabbits. Ophthalmoscopic imaging and optical coherence tomography (OCT) were used to validate the implants' placement.
Vitrectomy, followed by subretinal fluid injection for retinal detachment and retinotomy, allowed accurate placement of seven modules in the bleb, covering approximately a 3.5-mm diameter area on the retina via a single 1.5-mm retinotomy. OCT confirmed complete reattachment of the retina over the implants.
Subretinal implantation of multiple photovoltaic arrays via a single retinotomy, followed by their tiling, minimizes the scleral and retinal incisions and provides better fit to the spherical shape of the eye ball, compared to a single, larger module. Such minimally traumatic procedure can be performed with 20-gauge intraocular instruments.
建立用于恢复视力的多个光伏阵列视网膜下植入手术方法。
通过对兔进行单次视网膜切开术，将多个直径1毫米、厚度30微米的硅光伏阵列植入视网膜下。利用检眼镜成像和光学相干断层扫描（OCT）来验证植入物的位置。
玻璃体切割术，随后进行视网膜下液注射以造成视网膜脱离和视网膜切开术，使得能够通过单次1.5毫米视网膜切开术在泡内精确放置七个模块，覆盖视网膜上直径约3.5毫米的区域。OCT证实植入物上方的视网膜完全重新附着。
与单个较大模块相比，通过单次视网膜切开术进行多个光伏阵列的视网膜下植入并使其平铺，可将巩膜和视网膜切口最小化，并更好地贴合眼球的球形形状。这种微创操作可使用20号眼内器械进行。
