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经颅直流电刺激治疗儿童和青少年注意力缺陷多动障碍(ADHD):一项初步研究。

Transcranial Direct Current Stimulation in Children and Adolescents With Attention-Deficit/Hyperactivity Disorder (ADHD): A Pilot Study.

作者信息

Bandeira Igor Dórea, Guimarães Rachel Silvany Quadros, Jagersbacher João Gabriel, Barretto Thiago Lima, de Jesus-Silva Jéssica Regina, Santos Samantha Nunes, Argollo Nayara, Lucena Rita

机构信息

Department of Neuroscience and Mental Health, Medical School of Bahia, Federal University of Bahia, Salvador, Bahia, Brazil

Department of Neuroscience and Mental Health, Medical School of Bahia, Federal University of Bahia, Salvador, Bahia, Brazil.

出版信息

J Child Neurol. 2016 Jun;31(7):918-24. doi: 10.1177/0883073816630083. Epub 2016 Feb 15.

DOI:10.1177/0883073816630083
PMID:26879095
Abstract

Studies investigating the possible benefits of transcranial direct current stimulation on left dorsolateral prefrontal cortex in children and adolescents with attention-deficit hyperactivity disorder (ADHD) have not been performed. This study assesses the effect of transcranial direct current stimulation in children and adolescents with ADHD on neuropsychological tests of visual attention, visual and verbal working memory, and inhibitory control. An auto-matched clinical trial was performed involving transcranial direct current stimulation in children and adolescents with ADHD, using SNAP-IV and subtests Vocabulary and Cubes of the Wechsler Intelligence Scale for Children III (WISC-III). Subjects were assessed before and after transcranial direct current stimulation sessions with the Digit Span subtest of the WISC-III, inhibitory control subtest of the NEPSY-II, Corsi cubes, and the Visual Attention Test (TAVIS-3). There were 9 individuals with ADHD according to Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) criteria. There was statistically significant difference in some aspects of TAVIS-3 tests and the inhibitory control subtest of NEPSY-II. Transcranial direct current stimulation can be related to a more efficient processing speed, improved detection of stimuli, and improved ability to switch between an ongoing activity and a new one.

摘要

尚未开展关于经颅直流电刺激对患有注意力缺陷多动障碍(ADHD)的儿童和青少年左侧背外侧前额叶皮质可能产生的益处的研究。本研究评估经颅直流电刺激对患有ADHD的儿童和青少年在视觉注意力、视觉和言语工作记忆以及抑制控制的神经心理学测试方面的影响。进行了一项自动匹配的临床试验,对患有ADHD的儿童和青少年进行经颅直流电刺激,使用SNAP-IV以及韦氏儿童智力量表第三版(WISC-III)的词汇和方块子测验。在经颅直流电刺激疗程前后,使用WISC-III的数字广度子测验、NEPSY-II的抑制控制子测验、Corsi方块和视觉注意力测试(TAVIS-3)对受试者进行评估。根据《精神疾病诊断与统计手册》(第五版)标准,有9名患有ADHD的个体。在TAVIS-3测试的某些方面以及NEPSY-II的抑制控制子测验中存在统计学上的显著差异。经颅直流电刺激可能与更高效的处理速度、更好的刺激检测能力以及在进行中的活动和新活动之间切换的能力提高有关。

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