超声内镜引导下细针抽吸活检术对胰腺肿块病变的诊断价值。
Diagnostic potency of EUS-guided FNA for the evaluation of pancreatic mass lesions.
机构信息
Research Center for Gastroenterology and Liver Diseases, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
出版信息
Endosc Ultrasound. 2016 Jan-Feb;5(1):30-4. doi: 10.4103/2303-9027.175879.
BACKGROUND AND OBJECTIVES
Diagnosis of pancreatic lesions remains a clinical challenge. This study aimed to evaluate the diagnostic accuracy of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in pancreatic mass lesions.
PATIENTS AND METHODS
Clinical data, laboratory tests, and cytopathological and imaging reports were collected from 185 pancreatic EUS cases performed from March 2010 to January 2014. The final diagnosis was based on surgical findings, EUS-FNA or computed tomography (CT)-guided biopsy.
RESULTS
A total of 100 pancreatic FNAs were obtained by EUS. Most positive diagnoses of malignancy were pancreatic adenocarcinomas (n = 61). The site of pancreatic adenocarcinoma was the head in 50 (82.0%), body in seven (11.5%), and tail in four (6.5%). The sensitivity, specifi city, and positive and negative predictive values of EUS-FNA for diagnosing adenocarcinoma were 80.3%, 92.3%, 94.2%, and 75.0%, respectively.
DISCUSSION
We concluded that EUS-FNA of pancreatic lesion accurately diagnoses pancreatic adenocarcinoma and should be considered for the standard management of pancreatic adenocarcinoma.
背景与目的
胰腺病变的诊断仍然是临床挑战。本研究旨在评估超声内镜引导下细针抽吸（EUS-FNA）对胰腺肿块病变的诊断准确性。
患者与方法
收集了 2010 年 3 月至 2014 年 1 月期间进行的 185 例胰腺 EUS 病例的临床数据、实验室检查、细胞学和影像学报告。最终诊断基于手术发现、EUS-FNA 或 CT 引导下活检。
结果
总共通过 EUS 获得了 100 例胰腺细针抽吸物。大多数恶性肿瘤的阳性诊断为胰腺腺癌（n=61）。胰腺腺癌的部位为头部 50 例（82.0%）、体部 7 例（11.5%）和尾部 4 例（6.5%）。EUS-FNA 诊断腺癌的敏感性、特异性、阳性预测值和阴性预测值分别为 80.3%、92.3%、94.2%和 75.0%。
讨论
我们得出结论，EUS-FNA 对胰腺病变的诊断准确，应考虑作为胰腺腺癌的标准治疗方法。
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