Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacky University in Olomouc, 17 listopadu 1192/12, 771 46 Olomouc, Czech Republic.
Institute of Organic Chemistry and Biochemistry AS CR, v.v.i., Flemingovo nám. 2., 166 10 Prague 6, Czech Republic.
Nanoscale. 2016 Jun 16;8(24):12134-42. doi: 10.1039/c6nr00353b.
Graphene derivatives are promising materials for the electrochemical sensing of diverse biomolecules and development of new biosensors owing to their improved electron transfer kinetics compared to pristine graphene. Here, we report complex electrochemical behavior and electrocatalytic performance of variously fluorinated graphene derivatives prepared by reaction of graphene with a nitrogen-fluorine mixture at 2 bars pressure. The fluorine content was simply controlled by varying the reaction time and temperature. The studies revealed that electron transfer kinetics and electrocatalytic activity of CFx strongly depend on the degree of fluorination. The versatility of fluorinated graphene as a biosensor platform was demonstrated by cyclic voltammetry for different biomolecules essential in physiological processes, i.e. NADH, ascorbic acid and dopamine. Importantly, the highest electrochemical performance, even higher than pristine graphene, was obtained for fluorinated graphene with the lowest fluorine content (CF0.084) due to its high conductivity and enhanced adsorption properties combining π-π stacking interaction with graphene regions with hydrogen-bonding interaction with fluorine atoms.
石墨烯衍生物是电化学传感多种生物分子和开发新型生物传感器的有前途的材料，因为与原始石墨烯相比，它们具有改善的电子转移动力学。在这里，我们报告了通过在 2 巴压力下用氮氟混合物与石墨烯反应制备的各种氟化石墨烯衍生物的复杂电化学行为和电催化性能。氟含量通过改变反应时间和温度来简单控制。研究表明，CFx 的电子转移动力学和电催化活性强烈依赖于氟化程度。氟化石墨烯作为生物传感器平台的多功能性通过循环伏安法对生理过程中必需的不同生物分子（即 NADH、抗坏血酸和多巴胺）进行了证明。重要的是，由于其高导电性和增强的吸附性能，与具有氢键相互作用的氟原子的石墨烯区域结合的π-π堆积相互作用，具有最低氟含量（CF0.084）的氟化石墨烯获得了最高的电化学性能，甚至高于原始石墨烯。
