Evaluation of Aging and Health Status in Real Time Based on Routine Urinalysis Using an Automated Urine Analyzer.

BACKGROUND

To develop a quantitative system to enable straightforward objective assessment of health status in real time.

METHODS

On the basis of routine urinalysis with an automated urine analyzer, we obtained the urinalysis ill-health index (UIHI), which was the sum of urinary protein, pH, specific gravity, and color. Clinical laboratory parameters including stress indicators (neutrophilic leukocytes and glucose) and over-nutrition indicators (triglycerides, cholesterol, and uric acid) were monitored. The electrocardiography and blood pressure were also examined. A total of 1128 subjects were selected randomly from those who underwent physical examination to verify the UIHI.

RESULTS

The range of the UIHI score was 0 to 5. The cutoff value was 2.75. There were correlations of UIHI score with laboratory parameters and abnormal rates of BP and ECG. A greater UIHI score reflected worse health status (p < 0.05).

CONCLUSIONS

These data suggest that the UIHI can reflect the health status of an individual. It can be derived easily from routine urinalysis in a clinical laboratory and may be a useful tool for the quantitative differentiation of health status in real time.