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与普通处方和美容抗衰疗法相比,一种草本美容药妆品具有更高的疗效。

Superior Efficacy of an Herbal-based Cosmeceutical Compared With Common Prescription and Cosmetic Antiaging Therapies.

作者信息

Thornfeldt Carl R, Rizer Ronald L

出版信息

J Drugs Dermatol. 2016 Feb;15(2):218-23.

Abstract

INTRODUCTION

Research has shown that a disrupted stratum corneum permeability barrier coupled with chronic inflammation induce signs of extrinsic aging (photoaging). An novel herbal-based three product cosmeceutical regimen used to reverse these two anomalies that does not contain retinol, soy, niacinamide, tea, L-ascorbic acid or esters, hydroxy acids, tocopherol, or growth factors was tested in six human clinical trials to determine effectiveness and safety in reversing photoaging.

MATERIALS AND METHODS

Six randomized split face, double blind, prospective, controlled clinical trials involving a total of 110 subjects compared a cosmeceutical blend of novel herbs in regimens consisting of one to three products to several common antiaging topical treatments. These comparative products include prescription tretinoin, physician strength idebenone, kinetin, polyhydroxy, lactic and glycolic acids in reversing signs of photoaging.

RESULTS

The novel cosmeceutical blend regimen showed superior efficacy and safety in all six trials.

DISCUSSION

These trials substantiate that herbs not used in common antiaging products effectively and safely mitigate and reverse photoaging signs and symptoms. The novel concept of treating photoaging and preventing its progression by repairing and optimizing the stratum corneum barrier, while reversing and inhibiting chronic cutaneous inflammation, has now been proven.

摘要

引言

研究表明,角质层渗透屏障破坏与慢性炎症相结合会引发外在衰老(光老化)迹象。一种新型的基于草药的三产品药妆护肤方案用于逆转这两种异常情况,该方案不含视黄醇、大豆、烟酰胺、茶、L-抗坏血酸或其酯类、羟基酸、生育酚或生长因子,在六项人体临床试验中进行了测试,以确定其在逆转光老化方面的有效性和安全性。

材料与方法

六项随机半脸、双盲、前瞻性对照临床试验共涉及110名受试者,将一种包含一至三种产品的新型草药药妆混合物与几种常见的抗衰老外用治疗方法进行了比较。这些对照产品包括处方维甲酸、医用艾地苯醌、激动素、多羟基酸、乳酸和乙醇酸,用于逆转光老化迹象。

结果

在所有六项试验中,新型药妆混合物方案均显示出卓越的疗效和安全性。

讨论

这些试验证实,常见抗衰老产品中未使用的草药能够有效且安全地减轻和逆转光老化的体征和症状。通过修复和优化角质层屏障来治疗光老化并防止其进展,同时逆转和抑制慢性皮肤炎症这一新颖概念现已得到证实。

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