Trottmann M, Marcon J, D'Anastasi M, Bruce M F, Stief C G, Reiser M F, Buchner A, Clevert D A
Department of Urology, Ludwig-Maximilians-University of Munich-Grosshadern Campus, Munich, Germany.
Department of Clinical Radiology, Ludwig-Maximilians-University of Munich-Grosshadern Campus, Munich, Germany.
Clin Hemorheol Microcirc. 2016;62(3):273-81. doi: 10.3233/CH-162046.
Real-time shear-wave elastography (SWE) is a newly developed technique for the sonographic quantification of tissue elasticity, which already is used in the assessment of breast and thyroid lesions. Due to limited overlying tissue, the testes are ideally suited for assessment using shear wave elastography. To our knowledge, no published data exist on real-time SWE of the testes.
Sixty six male volunteers (mean age 51.86±18.82, range 20-86) with no known testicular pathology underwent normal B-mode sonography and multi-frame shear-wave elastography of both testes using the Aixplorer ® ultrasound system (SuperSonic Imagine, Aix en Provence, France). Three measurements were performed for each testis; one in the upper pole, in the middle portion and in the lower pole respectively. The results were statistically evaluated using multivariate analysis.
Mean shear-wave velocity values were similar in the inferior and superior part of the testicle (1.15 m/s) and were significantly lower in the centre (0.90 m/s). These values were age-independent. Testicular stiffness was significantly lower in the upper pole than in the rest of the testis with increasing volume (p = 0.007).
Real-time shear-wave elastography proved to be feasible in the assessment of testicular stiffness. It is important to consider the measurement region as standard values differ between the centre and the testicular periphery. Further studies with more subjects may be required to define the normal range of values for each age group. Useful clinical applications could include the diagnostic work-up of patients with scrotal masses or male infertility.
实时剪切波弹性成像(SWE)是一种新开发的用于超声量化组织弹性的技术,已用于评估乳腺和甲状腺病变。由于睾丸上方覆盖组织有限,睾丸非常适合使用剪切波弹性成像进行评估。据我们所知,目前尚无关于睾丸实时SWE的已发表数据。
66名无已知睾丸病变的男性志愿者(平均年龄51.86±18.82岁,范围20 - 86岁)接受了正常的B超检查,并使用Aixplorer®超声系统(法国普罗旺斯艾克斯的SuperSonic Imagine公司)对双侧睾丸进行了多帧剪切波弹性成像检查。每个睾丸进行三次测量,分别在上极、中部和下极进行。结果采用多变量分析进行统计学评估。
睾丸下部和上部的平均剪切波速度值相似(1.15米/秒),而中部显著较低(0.90米/秒)。这些值与年龄无关。随着体积增加,上极的睾丸硬度明显低于睾丸其他部位(p = 0.007)。
实时剪切波弹性成像被证明在评估睾丸硬度方面是可行的。由于中心和睾丸周边的标准值不同,因此考虑测量区域很重要。可能需要更多受试者的进一步研究来确定每个年龄组的正常数值范围。有用的临床应用可能包括阴囊肿块或男性不育患者的诊断检查。