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接触性空气变应原过敏在特应性皮炎中的作用。

The role of contact allergy to aeroallergens in atopic dermatitis.

作者信息

de Groot A C, Young E

机构信息

Department of Dermatology, Carolus & Willem-Alexander Hospital, MD's-Hertogenbosch, The Netherlands.

出版信息

Contact Dermatitis. 1989 Oct;21(4):209-14. doi: 10.1111/j.1600-0536.1989.tb03197.x.

DOI:10.1111/j.1600-0536.1989.tb03197.x
PMID:2689080
Abstract

In some patients with atopic dermatitis (AD), delayed-type allergy to aeroallergens, such as house dust mite, can be demonstrated by patch testing. Positive patch tests can be expected only in patients with AD and, in them, only to aeroallergens to which type 1 reactions have also been demonstrated. In an as yet unknown number of such cases, aeroallergens appear to play a role in AD. Studies to date have varied too widely in experimental method and design to allow more definite conclusions to be drawn. It is essential that future studies are standardised with regard to patch test system and designed to include adequate controls and assessment of relevance.

摘要

在一些特应性皮炎(AD)患者中,通过斑贴试验可证实对气传变应原(如屋尘螨)存在迟发型过敏反应。仅在AD患者中可预期出现阳性斑贴试验结果,而且在这些患者中,仅对已证实存在1型反应的气传变应原呈阳性。在数量尚不明的此类病例中,气传变应原似乎在AD中起作用。迄今为止的研究在实验方法和设计上差异太大,无法得出更明确的结论。至关重要的是,未来的研究应在斑贴试验系统方面进行标准化,并设计为纳入适当的对照和相关性评估。

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1
The role of contact allergy to aeroallergens in atopic dermatitis.接触性空气变应原过敏在特应性皮炎中的作用。
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2
Active participation of eosinophils in patch test reactions to inhalant allergens in patients with atopic dermatitis.
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Is the atopy patch test with house dust mites specific for atopic dermatitis?尘螨变应原皮肤点刺试验对特应性皮炎具有特异性吗?
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引用本文的文献

1
The Diagnostic Value of Delayed-Type Reactions to Perennial Aeroallergens for Atopic Disease.变应性疾病患者对常年气传过敏原迟发型反应的诊断价值。
Dermatitis. 2024 Jan-Feb;35(S1):S91-S97. doi: 10.1089/derm.2022.0050. Epub 2023 May 3.
2
Patch testing with dermatophagoides and its correlation with chronic eczema and atopic dermatitis.用尘螨进行斑贴试验及其与慢性湿疹和特应性皮炎的相关性。
Indian J Dermatol. 2009 Jul;54(3):243-6. doi: 10.4103/0019-5154.55633.
3
Aeroallergen contact dermatitis.气传变应原接触性皮炎
Clin Rev Allergy Immunol. 1996 Summer;14(2):209-23. doi: 10.1007/BF02780200.
4
Atopic dermatitis and delayed hypersensitivity to dust mites.特应性皮炎与对尘螨的迟发型超敏反应。
Clin Rev Allergy Immunol. 1995 Summer;13(2):161-72. doi: 10.1007/BF02758100.