Kapur Chetna, Shenoi Shrutakirthi D, Prabhu Smitha S, Balachandran C
Department of Skin and STD, Kasturba Medical College, Manipal, India.
Indian J Dermatol. 2009 Jul;54(3):243-6. doi: 10.4103/0019-5154.55633.
Chronic eczema is commonly encountered in the Indian set up. So also is atopic dermatitis. House dust mites (Dermatophagoides) are implicated in various diseases like atopic dermatitis, asthma, and perennial rhinitis. It has also been proven that patch testing with Dermatophagoides pteronyssinus (DP) is important for detection of contact sensitization in chronic dermatitis.
To study clinical characteristics of DP mix positive patients with regards to chronic dermatitis and atopic dermatitis.
Dermatology outpatients presenting to the department of Skin and STD of Kasturba Medical College (KMC), with clinically diagnosed atopic dermatitis and chronic eczema were chosen for the study. Inclusion and exclusion criteria were well demarked. Eighty six randomly selected patients of dermatitis were subjected to patch testing with standard series and DP mix.
Of the 86, 50 (58%) showed positive reaction to DP mix. Among these positive patients, chronic dermatitis was seen in 42 (84%) with involvement of exposed parts in 37 (74%). Atopic dermatitis was seen in 19 patients (38%) from DP positive group whereas it was observed in 4 patients (17%) from the other group.
Dermatophagoides mix positivity was statistically significant in chronic eczema as well as atopic dermatitis. Patch testing is an important tool to detect delayed type allergy to house dust mite.
在印度，慢性湿疹很常见。特应性皮炎也是如此。屋尘螨（尘螨属）与多种疾病有关，如特应性皮炎、哮喘和常年性鼻炎。也已证明，用屋尘螨（DP）进行斑贴试验对于检测慢性皮炎中的接触性致敏很重要。
研究DP混合阳性患者在慢性皮炎和特应性皮炎方面的临床特征。
选择就诊于卡斯图尔巴医学院（KMC）皮肤与性传播疾病科、临床诊断为特应性皮炎和慢性湿疹的皮肤科门诊患者进行研究。明确划分了纳入和排除标准。对86例随机选择的皮炎患者进行标准系列和DP混合斑贴试验。
86例患者中，50例（58%）对DP混合显示阳性反应。在这些阳性患者中，42例（84%）患有慢性皮炎，其中37例（74%）累及暴露部位。DP阳性组中有19例（38%）患有特应性皮炎，而另一组中有4例（17%）患有特应性皮炎。
在慢性湿疹和特应性皮炎中，屋尘螨混合阳性具有统计学意义。斑贴试验是检测对屋尘螨迟发型过敏的重要工具。
