Gerardi Viviana, Del Zompo Fabio, D'Aversa Francesca, Gasbarrini Antonio
Istituto di Medicina Interna e Gastroenterologia, Università Cattolica del Sacro Cuore, Roma.
G Ital Cardiol (Rome). 2016 Jan;17(1):11-4. doi: 10.1714/2140.23182.
The prevalence of cardiometabolic disorders (obesity, type 2 diabetes and cardiovascular disorders) is increasing globally and is a leading cause of mortality worldwide. Both genetics and environmental factors are involved in the pathogenesis of these disorders. Recent studies have shown that a state of dysbiosis may be implicated in body weight control, insulin resistance and cardio-metabolic risk factors, but the underlying mechanisms remain to be fully understood. Here we describe the possible role of the gut microbiota in cardiovascular diseases.
心血管代谢紊乱（肥胖、2型糖尿病和心血管疾病）在全球范围内的患病率正在上升，是全球主要的死亡原因。遗传因素和环境因素均参与这些疾病的发病机制。最近的研究表明，肠道菌群失调状态可能与体重控制、胰岛素抵抗和心血管代谢风险因素有关，但其潜在机制仍有待充分了解。在此，我们描述了肠道微生物群在心血管疾病中的可能作用。
