Yuan Su-Fen, Liu Ze-Hua, Huang Ri-Ping, Yin Hua, Dang Zhi
School of Environment and Energy, South China University of Technology, Guangzhou 510006, Guangdong, China and Key Lab of Pollution Control and Ecosystem Restoration in Industry Cluster, Ministry of Education, Guangzhou 510006, Guangdong, China E-mail:
Water Sci Technol. 2016;73(4):769-75. doi: 10.2166/wst.2015.526.
Due to lack of proper regulation, information about antibiotics consumption in many countries such as China is difficult to obtain. In this study, a simple method based on wastewater-based epidemiology was adopted to estimate their usage in four megacities of China. Six antibiotics (norfloxacin, ofloxacin, sulfamethoxazole, trimethoprim, erythromycin and roxithromycin), which are the most frequently consumed antibiotics in China, were selected as the targets. Based on our results, Chongqing had the largest total annual consumption of the selected six antibiotics among the four megacities, followed by Guangzhou, then Hong Kong, with Beijing having the least, with values of 4.4 g/y/P, 4.0 g/y/P, 1.6 g/y/P, and 1.3 g/y/P, respectively. Compared with the daily consumption per capita in Italy, the estimated consumption levels of the selected six antibiotics in four cities of China were 12-41 times those of Italy. Our results suggested that the consumption of antibiotics in China was excessive.
由于缺乏适当的监管，在中国等许多国家，有关抗生素消费的信息很难获取。在本研究中，采用了一种基于污水流行病学的简单方法来估算中国四个特大城市的抗生素使用情况。选择了六种在中国消费最频繁的抗生素（诺氟沙星、氧氟沙星、磺胺甲恶唑、甲氧苄啶、红霉素和罗红霉素）作为目标。根据我们的结果，在四个特大城市中，重庆所选六种抗生素的年总消费量最大，其次是广州，然后是香港，北京最少，分别为4.4克/年/人、4.0克/年/人、1.6克/年/人、和1.3克/年/人。与意大利的人均日消费量相比，中国四个城市所选六种抗生素的估计消费水平是意大利的12至41倍。我们的结果表明，中国的抗生素消费过量。
