Anadol Kelleci Ulker, Calhan Turan, Sahin Abdurrahman, Kahraman Resul, Ozdil Kamil, Sokmen Haci Mehmet, Yalcin Destina
Umraniye Education and Research Hospital, Department of Neurology, Umraniye, 34764 Istanbul, Turkey.
Mehmet Akif İnan Training and Research Hospital, Department of Gastroenterology, 63300 Şanlıurfa, Turkey.
Gastroenterol Res Pract. 2016;2016:6474651. doi: 10.1155/2016/6474651. Epub 2016 Jan 19.
Objectives. This study is aimed at studying the prevalence and characteristics of different types of headaches in patients with Crohn's disease. Materials and Methods. 51 patients in Crohn's disease group (F/M: 26/25) and 51 patients in control group (F/M: 27/24) were involved. Patients in Crohn's disease group were diagnosed and monitored according to European Crohn's and Colitis Organization diagnostic criteria. The control group composed of healthy subjects with similar age and sex to Crohn's disease group. Headache was classified using the International Headache Society II criteria. Results. Headache was reported by 35/51 (68.6%) patients in Crohn's disease group and 21/51 (41.2%) patients in the control group. The prevalence of headache was statistically high in the group with Crohn's disease (OR: 3.125 (95% CI: 1.38-7.04); p = 0.01). Comparing two groups with respect to their subtypes of headaches resulted in that the tension-type headache was statistically (p = 0.008) higher in Crohn's disease group (26/51) than in the control group (12/51). However, no significant difference was found in the migraine-type headache (p = 1). Conclusions. This study indicates that the prevalence of headache is high in patients with Crohn's disease and most commonly associated with the tension-type headache.
目的。本研究旨在探讨克罗恩病患者中不同类型头痛的患病率及特征。材料与方法。纳入克罗恩病组51例患者（女/男：26/25）和对照组51例患者（女/男：27/24）。克罗恩病组患者依据欧洲克罗恩病和结肠炎组织诊断标准进行诊断和监测。对照组由年龄和性别与克罗恩病组相似的健康受试者组成。采用国际头痛协会II标准对头痛进行分类。结果。克罗恩病组51例患者中有35例（68.6%）报告有头痛，对照组51例患者中有21例（41.2%）报告有头痛。克罗恩病组头痛患病率在统计学上较高（比值比：3.125（95%置信区间：1.38 - 7.04）；p = 0.01）。比较两组头痛亚型发现，克罗恩病组（26/51）紧张型头痛在统计学上（p = 0.008）高于对照组（12/51）。然而，偏头痛型头痛两组间无显著差异（p = 1）。结论。本研究表明，克罗恩病患者头痛患病率较高，且最常与紧张型头痛相关。
